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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL364398
Molecular formula	C23H37N3O3S
IUPAC name	2-[2,2-dioxo-1-[1-(4-propan-2-ylcyclohexyl)piperidin-4-yl]-4H-2lambda6,1,3-benzothiadiazin-3-yl]ethanol
Molecular weight	435.627
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.3
Synonyms	BDBM50153132 SCHEMBL3868218 2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-1,4-dihydro-2H-2lambda6-benzo[1,2,6]thiadiazin-3-yl}-ethanol
Inchi Key	AEXLHDOOHWXDNZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H37N3O3S/c1-18(2)19-7-9-21(10-8-19)24-13-11-22(12-14-24)26-23-6-4-3-5-20(23)17-25(15-16-27)30(26,28)29/h3-6,18-19,21-22,27H,7-17H2,1-2H3
PubChem CID	10137876
ChEMBL	CHEMBL364398
IUPHAR	N/A
BindingDB	50153132
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3937	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
3940	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
3938	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
3939	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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