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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3815013
Molecular formula	C25H34N4O2
IUPAC name	(3R)-7-hydroxy-N-[(2S)-3-methyl-1-(4-pyridin-4-ylpiperidin-1-yl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide
Molecular weight	422.573
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.0
Synonyms	N/A
Inchi Key	AFEWQFQXYDVMHB-DNQXCXABSA-N
Inchi ID	InChI=1S/C25H34N4O2/c1-17(2)24(16-29-11-7-19(8-12-29)18-5-9-26-10-6-18)28-25(31)23-14-20-3-4-22(30)13-21(20)15-27-23/h3-6,9-10,13,17,19,23-24,27,30H,7-8,11-12,14-16H2,1-2H3,(H,28,31)/t23-,24-/m1/s1
PubChem CID	127052129
ChEMBL	CHEMBL3815013
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521564	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
521563	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
521562	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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