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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL235154
Molecular formula	C22H21N3O2
IUPAC name	6-[[2-(2-phenylethyl)-1,3-dihydroisoindol-5-yl]oxy]pyridine-3-carboxamide
Molecular weight	359.429
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.0
Synonyms	SCHEMBL3696847 6-(2-phenethylisoindolin-5-yloxy)nicotinamide BDBM50226258 D04VJE
Inchi Key	ACAQNMZIFFSQCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H21N3O2/c23-22(26)17-7-9-21(24-13-17)27-20-8-6-18-14-25(15-19(18)12-20)11-10-16-4-2-1-3-5-16/h1-9,12-13H,10-11,14-15H2,(H2,23,26)
PubChem CID	44434061
ChEMBL	CHEMBL235154
IUPHAR	N/A
BindingDB	50226258
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1378	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
1379	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
1380	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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