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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 5A
Species	Homo sapiens (Human)
Gene	HTR5A
Synonym	5-HT5alpha 5-HT-5 MR22 Htr5 5-HT-5A 5-HT5A 5HT5- 5-HT5A receptor 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled serotonin receptor 5A [ Show all ]
Disease	N/A
Length	357
Amino acid sequence	MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
UniProt	P47898
Protein Data Bank	N/A
GPCR-HGmod model	P47898
3D structure model	This predicted structure model is from GPCR-EXP P47898.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3426
IUPHAR	10
DrugBank	BE0004688

Ligand

Name	Phencyclidine hydrochloride
Molecular formula	C17H26ClN
IUPAC name	1-(1-phenylcyclohexyl)piperidine;hydrochloride
Molecular weight	279.852
Hydrogen bond acceptor	1
Hydrogen bond donor	1
XlogP	None
Synonyms	D05453 MCV 4158 P-125 Phencyclidine Monohydrochloride Sernyl 6523AC AKOS015844481 CI-395 FT-0080143 NIH 9580 Phencyclidine HCl Phenylcyclidine hydrochloride SMR001338811 C.I. 395 CN-25,253-2 GP-121 NSC-40902 Phencyclidine hydrochloride [USAN] RW3111 V1JZQ7GDTX 1-(1-Phenylcyclohexyl)piperidine hydrochloride CHEMBL542581 DEA No. 7471 mcv4158 PCP hydrochloride Phencyclidine-d5 Hydrochloride Sernyl hydrochloride 956-90-1 API0007830 CI395 FT-0602418 nih9580 Piperidine, 1-(1-phenylcyclohexyl)-, hydrochloride Trank 1-(1-Phenylcyclohexyl) piperidine hydrochloride. C17H25N.HCl CN-25253-2 LS-115889 NSC40902 Phencyclidine hydrochloride, United States Pharmacopeia (USP) Reference Standard SCHEMBL21777 WLN: T6NTJ A- AL6TJ AR &GH 60124-79-0 CI 395 Elysion MLS002320664 pcphydrochloride PHENCYLIDINE HYDROCHLORIDE Sernylan AB0095424 AX8147413 Cl 395 hydrochloride GP 121 NSC 40902 Phencyclidine hydrochloride (USAN) QC-3096 UNII-V1JZQ7GDTX 1-(1-phenylcyclohexyl)-piperidinhydrochloride [ Show all ]
Inchi Key	BUAJNGPDPGKBGV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H25N.ClH/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18;/h1,4-5,10-11H,2-3,6-9,12-15H2;1H
PubChem CID	9795678
ChEMBL	CHEMBL542581
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<92517.0 nM	PubChem BioAssay data set	ChEMBL

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