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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL126737
Molecular formula	C21H22ClFN2O
IUPAC name	6-chloro-2-[3-(4-fluorophenoxy)propyl]-5-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
Molecular weight	372.868
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.7
Synonyms	6-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole BDBM50132102
Inchi Key	BERZXAZRUSUWMQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22ClFN2O/c1-24-20-10-12-25(11-3-13-26-16-8-6-15(23)7-9-16)14-18(20)17-4-2-5-19(22)21(17)24/h2,4-9H,3,10-14H2,1H3
PubChem CID	44351180
ChEMBL	CHEMBL126737
IUPHAR	N/A
BindingDB	50132102
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21856	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
21854	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
21855	5-hydroxytryptamine receptor 5A	P30966	Htr5a	Mus musculus (Mouse)	357
21857	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357

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