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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL476838
Molecular formula	C23H29FN2O5
IUPAC name	[3-(2-fluoroethoxy)-2-methoxyphenyl]-[1-[2-(4-nitrophenyl)ethyl]piperidin-4-yl]methanol
Molecular weight	432.492
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	3.9
Synonyms	BDBM50267509 (3-(2-Fluorethoxy)-2-methoxyphenyl)-(1-(2-p-nitrophenylethyl)-piperidine-4-yl)-methanol
Inchi Key	CFYAUZPZSBAQNA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H29FN2O5/c1-30-23-20(3-2-4-21(23)31-16-12-24)22(27)18-10-14-25(15-11-18)13-9-17-5-7-19(8-6-17)26(28)29/h2-8,18,22,27H,9-16H2,1H3
PubChem CID	44582677
ChEMBL	CHEMBL476838
IUPHAR	N/A
BindingDB	50267509
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41083	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
41075	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
41079	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
41082	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
41080	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
41081	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
41076	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
41077	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
41074	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
41078	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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