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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 5A
Species	Homo sapiens (Human)
Gene	HTR5A
Synonym	5-HT5alpha 5-HT-5 MR22 Htr5 5-HT-5A 5-HT5A 5HT5- 5-HT5A receptor 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled serotonin receptor 5A [ Show all ]
Disease	N/A
Length	357
Amino acid sequence	MDLPVNLTSFSLSTPSPLETNHSLGKDDLRPSSPLLSVFGVLILTLLGFLVAATFAWNLLVLATILRVRTFHRVPHNLVASMAVSDVLVAALVMPLSLVHELSGRRWQLGRRLCQLWIACDVLCCTASIWNVTAIALDRYWSITRHMEYTLRTRKCVSNVMIALTWALSAVISLAPLLFGWGETYSEGSEECQVSREPSYAVFSTVGAFYLPLCVVLFVYWKIYKAAKFRVGSRKTNSVSPISEAVEVKDSAKQPQMVFTVRHATVTFQPEGDTWREQKEQRAALMVGILIGVFVLCWIPFFLTELISPLCSCDIPAIWKSIFLWLGYSNSFFNPLIYTAFNKNYNSAFKNFFSRQH
UniProt	P47898
Protein Data Bank	N/A
GPCR-HGmod model	P47898
3D structure model	This predicted structure model is from GPCR-EXP P47898.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3426
IUPHAR	10
DrugBank	BE0004688

Ligand

Name	SMR000160814
Molecular formula	C24H18BrN3O4
IUPAC name	N-[(E)-[4-(2-anilino-2-oxoethoxy)-3-bromophenyl]methylideneamino]-1-benzofuran-2-carboxamide
Molecular weight	492.329
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.1
Synonyms	MolPort-019-756-141 N-[[4-(2-anilino-2-oxoethoxy)-3-bromophenyl]methylideneamino]-1-benzofuran-2-carboxamide BDBM41071 CHEMBL1968356 N-[(E)-[4-(2-anilino-2-oxo-ethoxy)-3-bromo-phenyl]methyleneamino]benzofuran-2-carboxamide STK192864 MLS000324461 N-[[3-bromanyl-4-(2-oxidanylidene-2-phenylazanyl-ethoxy)phenyl]methylideneamino]-1-benzofuran-2-carboxamide AC1OB2Y4 N-[(E)-[3-bromanyl-4-(2-oxidanylidene-2-phenylazanyl-ethoxy)phenyl]methylideneamino]-1-benzofuran-2-carboxamide N-[[4-(2-anilino-2-oxoethoxy)-3-bromophenyl]methylideneamino]-2-benzofurancarboxamide BDBM88849 cid_1018684 N-[(E)-[4-(2-anilino-2-oxoethoxy)-3-bromophenyl]methylideneamino]-1-benzofuran-2-carboxamide ZINC33334254 2-(4-{(E)-[2-(1-benzofuran-2-ylcarbonyl)hydrazinylidene]methyl}-2-bromophenoxy)-N-phenylacetamide MolPort-002-970-418 N-[[4-(2-anilino-2-keto-ethoxy)-3-bromo-benzylidene]amino]coumarilamide AKOS000333201 N-[(E)-[4-(2-anilino-2-keto-ethoxy)-3-bromo-benzylidene]amino]coumarilamide cid_6871588 N-[(E)-[4-(2-anilino-2-oxoethoxy)-3-bromophenyl]methylideneamino]-2-benzofurancarboxamide 2-{4-[2-(1-benzofuran-2-ylcarbonyl)carbohydrazonoyl]-2-bromophenoxy}-N-phenylacetamide [ Show all ]
Inchi Key	BIOLJPLPUJUMME-VULFUBBASA-N
Inchi ID	InChI=1S/C24H18BrN3O4/c25-19-12-16(10-11-21(19)31-15-23(29)27-18-7-2-1-3-8-18)14-26-28-24(30)22-13-17-6-4-5-9-20(17)32-22/h1-14H,15H2,(H,27,29)(H,28,30)/b26-14+
PubChem CID	6871588
ChEMBL	CHEMBL1968356
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<92466.0 nM	PubChem BioAssay data set	ChEMBL

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