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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL446459
Molecular formula	C14H19F2N3O
IUPAC name	N-(2,2-difluoroethyl)-4-methyl-8-propan-2-yloxy-3,4-dihydro-1H-quinazolin-2-imine
Molecular weight	283.323
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.6
Synonyms	BDBM50371980 SCHEMBL1379614
Inchi Key	ADOGGHZNEGBRNB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H19F2N3O/c1-8(2)20-11-6-4-5-10-9(3)18-14(19-13(10)11)17-7-12(15)16/h4-6,8-9,12H,7H2,1-3H3,(H2,17,18,19)
PubChem CID	135458427
ChEMBL	CHEMBL446459
IUPHAR	N/A
BindingDB	50371980
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
2915	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
2914	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
2917	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
2916	5-hydroxytryptamine receptor 5A	P47898	HTR5A	Homo sapiens (Human)	357
2918	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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