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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000102159
Molecular formula	C19H23FN2O2
IUPAC name	1-[(2,4-dimethoxyphenyl)methyl]-4-(2-fluorophenyl)piperazine
Molecular weight	330.403
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.4
Synonyms	Cambridge id 5262294 Oprea1_566622 1-[(2,4-dimethoxyphenyl)methyl]-4-(2-fluorophenyl)piperazine cid_2173523 SR-01000201868 AC1M2L9M MLS000105278 REGID_for_CID_2173523 HMS2427D19 SR-01000201868-1 BDBM31037 MolPort-002-083-957 1-(2,4-dimethoxybenzyl)-4-(2-fluorophenyl)piperazine CHEMBL1606397 AB00077529-01 MCULE-7819278371 ZINC2811204 [ Show all ]
Inchi Key	FTXHIWXQEQZCKC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23FN2O2/c1-23-16-8-7-15(19(13-16)24-2)14-21-9-11-22(12-10-21)18-6-4-3-5-17(18)20/h3-8,13H,9-12,14H2,1-2H3
PubChem CID	2173523
ChEMBL	CHEMBL1606397
IUPHAR	N/A
BindingDB	31037
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
87215	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
87217	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
87214	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
87216	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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