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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7-Hydroxy Risperidone
Molecular formula	C23H27FN4O3
IUPAC name	3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-7-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
Molecular weight	426.492
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	1.7
Synonyms	ACMC-20bpx3 GTPL67 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-7-hydroxy-2-methyl-4H-pyrido[1,2-a]-pyrimidin-4-one CHEMBL3542429 PDSP2_001541 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-7-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one 9-Hydroxy-risperidone AC1Q69BX DTXSID50332989 SCHEMBL206059 4H-Pyrido[1,2-a]pyrimidin-4-one,3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-7-hydroxy-2-methyl- AKOS030255680 J-008382 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-7-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one 7-Hydroxy Risperidone-d4 CTK4C5514 R 79242 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-7-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one ABWPQNZPAOAQSG-UHFFFAOYSA-N ACM1215454048 FT-0670099 147663-04-5 API0000325 PDSP1_001557 3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)-1-piperidyl]ethyl]-7-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one 7-ydroxyrisperidone D0Y4MC RT-010827 3-{2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidin-1-yl]ethyl}-7-hydroxy-2-methyl-6,7,8,9-tetrahydro-4h-pyrido[1,2-a]pyrimidin-4-one AC1L9S9M [ Show all ]
Inchi Key	ABWPQNZPAOAQSG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27FN4O3/c1-14-18(23(30)28-13-17(29)3-5-21(28)25-14)8-11-27-9-6-15(7-10-27)22-19-4-2-16(24)12-20(19)31-26-22/h2,4,12,15,17,29H,3,5-11,13H2,1H3
PubChem CID	475100
ChEMBL	N/A
IUPHAR	67
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553253	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
553251	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
553252	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
553250	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
553254	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
553255	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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