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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SB 204070 hydrochloride
Molecular formula	C19H27ClN2O4
IUPAC name	(1-butylpiperidin-4-yl)methyl 5-amino-6-chloro-2,3-dihydro-1,4-benzodioxine-8-carboxylate
Molecular weight	382.885
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.5
Synonyms	SCHEMBL1041174 (1-Butyl-4-piperidyl)methyl 5-amino-4-chloro-7,10-dioxabicyclo[4.4.0]deca-2,4,11-triene-2-carboxylate AKOS027422837 GTPL256 NCGC00162328-01 CCG-205125 Lopac-S-3313 PDSP2_001665 (1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-2,3-dihydro-1,4-benzodioxine-5-carboxylate D0N8EL NCGC00015946-01 SB-204070 ZINC1536586 (1-butylpiperidin-4-yl)methyl 5-amino-6-chloro-2,3-dihydro-1,4-benzodioxine-8-carboxylate BDBM82505 KB-272760 NSC_121881 148702-58-3 Lopac0_001048 SB204070 (1-butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate AC1L3TKM DTXSID90164069 NCGC00015946-02 (1-n-butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate CAS_121881 L000653 PDSP1_001682 CHEMBL68131 LS-187292 SB-204,070 [ Show all ]
Inchi Key	AOOSJYIINXVNHV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H27ClN2O4/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18/h11,13H,2-10,12,21H2,1H3
PubChem CID	121881
ChEMBL	CHEMBL68131
IUPHAR	256
BindingDB	82505
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
10451	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
10441	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
10448	5-hydroxytryptamine receptor 1D	Q60484	HTR1D	Cavia porcellus (Guinea pig)	376
10439	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
10440	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
10438	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
10434	5-hydroxytryptamine receptor 4	Q13639	HTR4	Homo sapiens (Human)	388
10437	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
10446	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
10449	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
10442	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
10447	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
10436	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
10443	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
10445	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
10450	D(1A) dopamine receptor	Q61616	Drd1	Mus musculus (Mouse)	446
10444	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
10433	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
10435	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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