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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL76237
Molecular formula	C19H22N2O3S
IUPAC name	2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine
Molecular weight	358.456
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.5
Synonyms	AC1OCFKC NCGC00371046-02 PDSP2_000370 263384-65-2 MS245 ZINC13553349 BDBM34141 PDSP1_000372 2-[1-(benzenesulfonyl)-5-methoxyindol-3-yl]-N,N-dimethylethanamine KB-78965 PDSP2_000371 N,N-Dimethyl-1-(phenylsulfonyl)-5-methoxy-1H-indole-3-ethanamine PDSP1_000373 2-[5-methoxy-1-(phenylsulfonyl)-1h-indol-3-yl]-N,N-dimethylethanamine MS-245 SCHEMBL5499070 [ Show all ]
Inchi Key	AIJIQCBYMBZLJD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H22N2O3S/c1-20(2)12-11-15-14-21(19-10-9-16(24-3)13-18(15)19)25(22,23)17-7-5-4-6-8-17/h4-10,13-14H,11-12H2,1-3H3
PubChem CID	6918542
ChEMBL	CHEMBL76237
IUPHAR	N/A
BindingDB	34141
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6276	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
6275	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
6279	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
6273	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
6278	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
6277	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
6267	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
6268	5-hydroxytryptamine receptor 5A	P35364	Htr5a	Rattus norvegicus (Rat)	357
6269	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
6274	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
6270	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
6272	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
6271	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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