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You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
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Ligand

Name	spiperone
Molecular formula	C23H26FN3O2
IUPAC name	8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	395.478
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.0
Synonyms	NCGC00015964-12 AC1L1JYU NCGC00022260-07 BRN 0632204 Pharmakon1600-01501152 R-5147 DSSTox_CID_25205 SPECTRUM1501152 FT-0674639 Spiperone [USAN:INN:BAN:JAN] HMS2235E11 KBio2_006759 1-(4-Fluorophenyl)-4-(4-hydroxy-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-en-8-yl)-1-butanone # MCULE-7534168791 4-Phenyl-8-[3-(4-fluorobenzoyl)propyl]-1-oxo-2,4,8-triazaspiro[4,5]decane NCGC00015964-04 8-[4-(4-fluorophenyl)-4-oxidanylidene-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one Spiropitan (TN) UNII-4X6E73CJ0Q NCGC00016536-01 BDBM21397 NSC-170983 Butyrophenone, 4'-fluoro-4-(4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decan-8-yl)- Prestwick2_000288 D01051 SBI-0051039.P003 DTXSID5045205 Spectrum4_000451 HMS1568J18 Spiperonum [INN-Latin] HMS501M08 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(4-(4-fluorophenyl)-4-oxobutyl)-1-phenyl- KBioSS_001623 36693-EP2272537A2 MLS001076321 8-(3-(p-Fluorobenzoyl)propyl)-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one NCGC00015964-07 8-[4-(4-fluorophenyl)-4-oxobutyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one SR-01000000261-8 [3H]-spiperone AB00052224-15 NCGC00022260-05 BRD-K55468218-001-05-5 NSC757864 CCG-38975 R 5147 DivK1c_000566 SPBio_001532 Espiperona HMS2092H17 KBio2_001623 1,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorobenzoyl)propyl]-1-phenyl- Lopac0_001069 36693-EP2311803A1 NCGC00015964-02 8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,8-triazaspiro[4.5]decan-4-one NCGC00015964-10 Spiroperone Tox21_110269 NCGC00015964-13 AKOS024282958 NINDS_000566 BSPBio_000196 Prestwick0_000288 CHEMBL267930 regid855701 DSSTox_GSID_45205 Spectrum2_001426 GTPL3300 Spiperone, solid HMS3371L01 KBio3_002459 MFCD00055099 4X6E73CJ0Q NCGC00015964-05 8-[4-(4-fluorophenyl)-4-oxo-butyl]-4-phenyl-2,4,8-triazaspiro[4.5]decan-1-one SR-01000000261 WLN: T6N DXTJ A3VR DF& D-& CT5MVXN EHJ DR NCGC00022260-02 BN0500 NSC-757864 C23H26FN3O2 Prestwick3_000288 D04TIH SCHEMBL116031 E 525 Spectrum5_000987 HMS1921L09 IDI1_000566 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[3-(p-fluorobenzoyl)propyl]-1-phenyl- L000569 36693-EP2311801A1 MolPort-003-666-371 8-(3-p-Fluorobenzoyl-1-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro(4,5)decane NCGC00015964-08 Spiroperidol ST059306 [3H]-Spiroperidol AB00052224_16 NCGC00022260-06 BRD-K55468218-003-01-0 Opera_ID_1551 CHEBI:9233 R 5147, Spiroperidol DKGZKTPJOSAWFA-UHFFFAOYSA-N SPBio_002415 Espiperona [INN-Spanish] Spiperone (JAN/USAN) HMS2095J18 KBio2_004191 1,8-Triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl- LS-154780 36693-EP2371814A1 NCGC00015964-03 8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one NCGC00015964-11 Spiropitan Tox21_110269_1 NCGC00015964-17 API0004229 NSC 170983 BSPBio_002959 Prestwick1_000288 cid_5265 REGID_for_CID_5265 DSSTox_RID_80749 Spectrum3_001460 GTPL99 Spiperonum HMS3712J18 1,3,8-Triazaspiro(4.5)decan-4-one, 8-(3-(p-fluorobenzoyl)propyl)-1-phenyl- KBioGR_000862 MLS000028615 749-02-0 NCGC00015964-06 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one SR-01000000261-5 ZINC643233 AB00052224 NCGC00022260-04 BPBio1_000216 NSC170983 CAS-749-02-0 Prestwick_624 D05EQG SMR000058674 EINECS 212-024-0 Spectrum_001143 HMS2089E16 KBio1_000566 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl- Lopac-S-7395 36693-EP2311802A1 NCGC00015964-01 8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one NCGC00015964-09 Spiroperidone Tocris-0995 [3H]spiperone [ Show all ]
Inchi Key	DKGZKTPJOSAWFA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
PubChem CID	5265
ChEMBL	CHEMBL267930
IUPHAR	99, 3300
BindingDB	21397
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
62205	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
62217	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
62203	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
62234	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
553558	5-hydroxytryptamine receptor 1B	P28334	Htr1b	Mus musculus (Mouse)	386
62215	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
62230	5-hydroxytryptamine receptor 1D	P79400	HTR1D	Sus scrofa (Pig)	291
62233	5-hydroxytryptamine receptor 1D	P11614	HTR1D	Canis lupus familiaris (Dog)	377
62235	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
62202	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
62228	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
62211	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
62214	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
62224	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
62227	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
62191	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
62198	5-hydroxytryptamine receptor 2B	P30994	Htr2b	Rattus norvegicus (Rat)	479
555715	5-hydroxytryptamine receptor 2B	Q02152	Htr2b	Mus musculus (Mouse)	479
62209	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
62226	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460

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