You can:
| Name | 5-hydroxytryptamine receptor 2A |
|---|---|
| Species | Sus scrofa (Pig) |
| Gene | HTR2A |
| Synonym | 5-HT-2 5-HT-2A 5-HT2A Serotonin receptor 2A |
| Disease | N/A for non-human GPCRs |
| Length | 470 |
| Amino acid sequence | MDVLCEENTSLSSPTNSFMQLNDDTRLYHNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPPCFSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHRRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENKKPLQLILVNTIPALAYKSSQLQTGQKENSKQDDKATENDCTMVALGKQHSEDAPADNSNTVNEKVSCV |
| UniProt | P50129 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2490 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 125 |  CHEMBL1256170 | C41H45NO | 567.817 | 2 / 0 | 9.2 | No |
| 634 |  CHEMBL1258494 | C24H33N3O2 | 395.547 | 4 / 1 | 4.2 | Yes |
| 5031 |  CHEMBL211135 | C17H17Cl2N5 | 362.258 | 4 / 0 | 3.4 | Yes |
| 8376 |  CHEMBL272602 | C18H20N4O | 308.385 | 4 / 1 | 2.1 | Yes |
| 8940 |  CHEMBL1771110 | C28H33N3O2S | 475.651 | 5 / 0 | 5.1 | No |
| 11069 |  tryptamine | C10H12N2 | 160.22 | 1 / 2 | 1.6 | Yes |
| 11191 |  CHEMBL2113718 | C16H18N4 | 266.348 | 3 / 1 | 2.2 | Yes |
| 12463 |  1-Isopropyltryptamine | C13H18N2 | 202.301 | 1 / 1 | 2.0 | Yes |
| 13819 |  CHEMBL380330 | C19H23NO | 281.399 | 2 / 0 | 4.1 | Yes |
| 17032 |  CHEMBL240376 | C25H31N3O2 | 405.542 | 4 / 1 | 4.1 | Yes |
| 24113 |  CHEMBL239733 | C24H27Cl2N3O | 444.4 | 3 / 1 | 5.4 | No |
| 24263 |  CHEMBL380054 | C18H19FN4 | 310.376 | 4 / 0 | 3.3 | Yes |
| 26648 |  CHEBI:48565 | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 35283 |  CHEMBL201525 | C18H21N | 251.373 | 1 / 0 | 4.6 | Yes |
| 39769 |  CHEMBL405292 | C17H18FN5 | 311.364 | 5 / 0 | 2.2 | Yes |
| 39863 |  CHEMBL1258383 | C25H31N3OS | 421.603 | 4 / 1 | 5.6 | No |
| 46115 |  CHEMBL389357 | C20H25NO | 295.426 | 2 / 0 | 4.5 | Yes |
| 47911 |  CHEMBL391256 | C24H29N3O2 | 391.515 | 4 / 1 | 3.8 | Yes |
| 48192 |  CHEMBL241212 | C24H29N3O2 | 391.515 | 4 / 1 | 3.8 | Yes |
| 51699 |  CHEMBL378680 | C18H18Cl2N4 | 361.27 | 3 / 0 | 4.5 | Yes |
| 56547 |  CHEMBL272873 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
| 62224 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 66163 |  CHEMBL574569 | C62H70N12O4 | 1047.32 | 12 / 2 | 8.8 | No |
| 66875 |  CHEMBL1257811 | C23H28ClNO2 | 385.932 | 3 / 1 | 3.9 | Yes |
| 68618 |  FAUC 213 | C18H19ClN4 | 326.828 | 3 / 0 | 3.2 | Yes |
| 72149 |  CHEMBL391042 | C25H31N3O2 | 405.542 | 4 / 1 | 4.1 | Yes |
| 80457 |  CHEMBL256492 | C21H27FN2O3 | 374.456 | 6 / 0 | 3.6 | Yes |
| 82399 |  CHEMBL1258036 | C30H33FN2O | 456.605 | 4 / 0 | 6.1 | No |
| 83259 |  CHEMBL241438 | C31H35N3O2 | 481.64 | 4 / 1 | 5.9 | No |
| 83870 |  Ketanserin | C22H22FN3O3 | 395.434 | 5 / 1 | 2.6 | Yes |
| 86999 |  CHEMBL270408 | C20H25FN2O2 | 344.43 | 5 / 0 | 3.6 | Yes |
| 91500 |  CHEMBL405260 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
| 93545 |  CHEMBL407818 | C18H20N4O | 308.385 | 4 / 1 | 2.1 | Yes |
| 98178 |  CHEMBL241424 | C30H33N3O2 | 467.613 | 4 / 1 | 5.5 | No |
| 101207 |  LY86057 | C20H26N2O3 | 342.439 | 4 / 2 | 2.4 | Yes |
| 104571 |  CHEMBL378515 | C18H20ClN5O | 357.842 | 5 / 0 | 2.7 | Yes |
| 105786 |  CHEMBL1258999 | C22H24FN3O2 | 381.451 | 5 / 1 | 2.9 | Yes |
| 115691 |  CHEMBL1258382 | C33H37N3OS | 523.739 | 4 / 1 | 7.4 | No |
| 119242 |  CHEMBL2207632 | C24H24N2O | 356.469 | 3 / 0 | 4.6 | Yes |
| 122079 |  CHEMBL2207637 | C25H31N3O | 389.543 | 4 / 0 | 4.1 | Yes |
| 124934 |  CHEMBL2207641 | C34H40N4O2 | 536.72 | 6 / 0 | 5.7 | No |
| 125626 |  CHEMBL231070 | C19H23NO | 281.399 | 2 / 1 | 4.2 | Yes |
| 129088 |  CHEMBL276778 | C20H25NO | 295.426 | 2 / 0 | 4.5 | Yes |
| 446835 |  CHEMBL241211 | C27H25Cl2N3O | 478.417 | 3 / 1 | 6.1 | No |
| 131354 |  prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
| 134926 |  CHEMBL1256169 | C41H45NO2 | 583.816 | 3 / 1 | 8.1 | No |
| 135141 |  CHEMBL56118 | C16H18N4 | 266.348 | 3 / 1 | 1.9 | Yes |
| 136084 |  Abt-418 | C9H14N2O | 166.224 | 3 / 0 | 1.2 | Yes |
| 137702 |  CHEMBL272073 | C19H22ClFN2O | 348.846 | 4 / 0 | 4.3 | Yes |
| 137869 |  CHEMBL2207638 | C28H35N3O | 429.608 | 4 / 0 | 5.0 | Yes |
| 141018 |  CHEMBL255163 | C19H22ClFN2O | 348.846 | 4 / 0 | 4.3 | Yes |
| 447440 |  CHEMBL241641 | C29H29Cl2N3O | 506.471 | 3 / 1 | 6.8 | No |
| 154020 |  BDBM86527 | C18H26N4O2S | 362.492 | 5 / 1 | 1.4 | Yes |
| 154039 |  Mesulergine | C18H26N4O2S | 362.492 | 5 / 1 | 1.4 | Yes |
| 157765 |  AC1L1H4K | C23H32N2O3 | 384.52 | 4 / 1 | 3.1 | Yes |
| 157858 |  CHEMBL508399 | C19H23NO | 281.399 | 2 / 1 | 4.2 | Yes |
| 159348 |  5-METHOXYTRYPTAMINE | C11H14N2O | 190.246 | 2 / 2 | 0.5 | Yes |
| 167209 |  BDBM82516 | C25H35N3O | 393.575 | 2 / 1 | 4.1 | Yes |
| 167270 |  CHEMBL574534 | C62H70N12O4 | 1047.32 | 12 / 2 | 8.8 | No |
| 167866 |  CHEMBL424294 | C24H29N3O2S | 423.575 | 5 / 1 | 4.9 | Yes |
| 173048 |  CHEMBL2207633 | C30H28N2O | 432.567 | 3 / 0 | 6.3 | No |
| 173985 |  LY-193525 | C22H29N3O | 351.494 | 2 / 2 | 3.5 | Yes |
| 174650 |  CHEMBL270406 | C22H29FN2O4 | 404.482 | 7 / 0 | 3.6 | Yes |
| 174856 |  1-Methyllysergic acid butanolamide | C21H27N3O2 | 353.466 | 3 / 2 | 2.3 | Yes |
| 175649 |  sumatriptan | C14H21N3O2S | 295.401 | 4 / 2 | 0.9 | Yes |
| 176257 |  CHEMBL203637 | C18H20ClNO | 301.814 | 2 / 1 | 4.4 | Yes |
| 191545 |  haloperidol | C21H23ClFNO2 | 375.868 | 4 / 1 | 3.2 | Yes |
| 192539 |  CHEMBL1258154 | C30H33ClN2O | 473.057 | 3 / 0 | 6.7 | No |
| 193792 |  CHEMBL2207636 | C23H23N3O | 357.457 | 4 / 0 | 4.0 | Yes |
| 200832 |  CHEMBL1256171 | C41H47N3O | 597.847 | 3 / 1 | 8.6 | No |
| 210104 |  CHEMBL2207643 | C22H24N2O | 332.447 | 3 / 0 | 4.3 | Yes |
| 214509 |  CHEMBL272853 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
| 217071 |  CHEMBL1258495 | C25H35N3O | 393.575 | 3 / 1 | 5.0 | Yes |
| 218485 |  CHEMBL1923416 | C18H20FN3O2 | 329.375 | 6 / 0 | 2.4 | Yes |
| 221144 |  CHEMBL1771109 | C28H33N3O3 | 459.59 | 5 / 0 | 4.5 | Yes |
| 228261 |  HMS3266K12 | C24H29N3O6 | 455.511 | 7 / 5 | N/A | N/A |
| 230245 |  LY-197541 | C24H34N2O3 | 398.547 | 4 / 1 | 3.6 | Yes |
| 231199 |  CHEMBL212370 | C18H19ClN4 | 326.828 | 3 / 0 | 3.9 | Yes |
| 232653 |  CHEMBL2207635 | C23H26N2O2 | 362.473 | 4 / 1 | 3.4 | Yes |
| 238258 |  CHEMBL201170 | C18H21NO | 267.372 | 2 / 1 | 3.8 | Yes |
| 238882 |  CHEMBL272396 | C17H18BrN5 | 372.27 | 4 / 0 | 2.8 | Yes |
| 239080 |  CHEMBL1923292 | C19H21FN2O2 | 328.387 | 5 / 0 | 3.2 | Yes |
| 240586 |  Phentolamine mesylate | C18H23N3O4S | 377.459 | 6 / 3 | N/A | N/A |
| 244175 |  CHEMBL1771105 | C26H35N3O3 | 437.584 | 5 / 0 | 4.1 | Yes |
| 249045 |  CHEMBL1923293 | C20H23FN2O3 | 358.413 | 6 / 0 | 3.1 | Yes |
| 252883 |  CHEMBL1771111 | C29H35N3O2S | 489.678 | 5 / 0 | 5.4 | No |
| 258443 |  CHEMBL1771112 | C29H34N4O2 | 470.617 | 5 / 0 | 4.3 | Yes |
| 262384 |  Befiradol | C20H22ClF2N3O | 393.863 | 5 / 1 | 3.2 | Yes |
| 263039 |  CHEMBL2207640 | C28H36N4O | 444.623 | 5 / 0 | 4.0 | Yes |
| 270655 |  CHEMBL270056 | C17H18FN5 | 311.364 | 5 / 0 | 2.2 | Yes |
| 272524 |  CHEMBL1258155 | C23H28ClNO | 369.933 | 2 / 0 | 5.5 | No |
| 273152 |  HEAT | C19H21NO2 | 295.382 | 3 / 2 | 3.8 | Yes |
| 277676 |  CHEMBL212631 | C19H22N4O | 322.412 | 4 / 0 | 3.2 | Yes |
| 283916 |  CHEMBL1258270 | C25H33NO | 363.545 | 2 / 0 | 5.6 | No |
| 290324 |  serotonin | C10H12N2O | 176.219 | 2 / 3 | 0.2 | Yes |
| 294951 |  CHEMBL241436 | C29H29Cl2N3O | 506.471 | 3 / 1 | 6.8 | No |
| 295179 |  CHEMBL411437 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
| 299423 |  CHEMBL271513 | C20H25FN2O2 | 344.43 | 5 / 0 | 3.6 | Yes |
| 299590 |  CHEMBL2207639 | C27H33N3O2 | 431.58 | 5 / 0 | 3.8 | Yes |
| 300199 |  CHEMBL272395 | C17H18BrN5 | 372.27 | 4 / 0 | 2.8 | Yes |
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