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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL424294
Molecular formula	C24H29N3O2S
IUPAC name	N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Molecular weight	423.575
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.9
Synonyms	N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide BDBM50119386 SCHEMBL5507438 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide FAUC-346
Inchi Key	KFMBPIZMZUDONQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29N3O2S/c1-29-21-10-4-3-9-20(21)27-16-14-26(15-17-27)13-7-6-12-25-24(28)23-18-19-8-2-5-11-22(19)30-23/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,25,28)
PubChem CID	9888555
ChEMBL	CHEMBL424294
IUPHAR	N/A
BindingDB	50119386
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
167867	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
167866	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
483687	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
167865	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
167868	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
167864	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
167863	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
167862	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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