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Name | D(1A) dopamine receptor |
---|---|
Species | Sus scrofa (Pig) |
Gene | DRD1 |
Synonym | Dopamine D1 receptor |
Disease | N/A for non-human GPCRs |
Length | 446 |
Amino acid sequence | MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT |
UniProt | P50130 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5067 |
IUPHAR | N/A |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
126 | CHEMBL1256170 | C41H45NO | 567.817 | 2 / 0 | 9.2 | No |
633 | CHEMBL1258494 | C24H33N3O2 | 395.547 | 4 / 1 | 4.2 | Yes |
1584 | CHEMBL207543 | C22H26Cl2N6 | 445.392 | 5 / 0 | 4.3 | Yes |
441750 | CHEMBL558838 | C21H28N6O | 380.496 | 6 / 1 | 2.9 | Yes |
5033 | CHEMBL211135 | C17H17Cl2N5 | 362.258 | 4 / 0 | 3.4 | Yes |
5238 | CHEMBL196744 | C21H24Cl2FN3O | 424.341 | 4 / 1 | 4.9 | Yes |
8375 | CHEMBL272602 | C18H20N4O | 308.385 | 4 / 1 | 2.1 | Yes |
8939 | CHEMBL1771110 | C28H33N3O2S | 475.651 | 5 / 0 | 5.1 | No |
8994 | CHEMBL1928132 | C62H92N6O13 | 1129.45 | 17 / 2 | 5.1 | No |
442128 | CHEMBL3318840 | C58H72Cl2F2N2O6 | 1002.12 | 10 / 0 | 14.6 | No |
17030 | CHEMBL240376 | C25H31N3O2 | 405.542 | 4 / 1 | 4.1 | Yes |
18844 | CHEMBL182379 | C24H28IN3O3 | 533.41 | 5 / 1 | 4.9 | No |
19402 | CHEMBL1928119 | C25H35N3O4 | 441.572 | 6 / 1 | 3.3 | Yes |
19693 | CHEMBL1928135 | C27H37N5O4 | 495.624 | 7 / 1 | 2.2 | Yes |
22054 | CHEMBL1928133 | C26H35N5O4 | 481.597 | 7 / 1 | 2.5 | Yes |
23144 | CHEMBL1928248 | C54H76N6O9 | 953.235 | 13 / 2 | 5.7 | No |
23242 | DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
23512 | CHEMBL2443000 | C20H30FN5O3 | 407.49 | 8 / 0 | 1.1 | Yes |
24112 | CHEMBL239733 | C24H27Cl2N3O | 444.4 | 3 / 1 | 5.4 | No |
24261 | CHEMBL380054 | C18H19FN4 | 310.376 | 4 / 0 | 3.3 | Yes |
31571 | CHEMBL211539 | C20H23BrN4O | 415.335 | 4 / 0 | 4.3 | Yes |
34184 | CHEMBL210404 | C20H23N5O | 349.438 | 5 / 0 | 2.6 | Yes |
443081 | CHEMBL3318846 | C52H60Cl2F2N4O6 | 945.971 | 12 / 0 | 8.3 | No |
36125 | CHEMBL1928126 | C54H76N6O9 | 953.235 | 13 / 2 | 5.7 | No |
36461 | CHEMBL212160 | C22H24N6O | 388.475 | 5 / 0 | 3.5 | Yes |
37348 | CID 29982233 | C15H21IN2O3 | 404.248 | 3 / 2 | 2.9 | Yes |
37446 | CHEMBL1803054 | C50H72N10O5 | 893.191 | 13 / 0 | 7.2 | No |
37567 | CHEMBL210551 | C23H26N6O | 402.502 | 5 / 0 | 3.5 | Yes |
39369 | CHEMBL484203 | C19H30N4 | 314.477 | 3 / 0 | 3.6 | Yes |
39771 | CHEMBL405292 | C17H18FN5 | 311.364 | 5 / 0 | 2.2 | Yes |
39864 | CHEMBL1258383 | C25H31N3OS | 421.603 | 4 / 1 | 5.6 | No |
443425 | CHEMBL560125 | C18H21N5O | 323.4 | 5 / 0 | 2.5 | Yes |
45132 | CHEMBL1803025 | C58H80N10O6 | 1013.34 | 14 / 0 | 10.0 | No |
443563 | CHEMBL3318852 | C21H21ClFNO3 | 389.851 | 4 / 1 | 2.9 | Yes |
47680 | fauc-365 | C23H25Cl2N3OS | 462.433 | 4 / 1 | 6.2 | No |
47684 | CHEMBL362101 | C19H22Cl2IN3OS | 538.269 | 4 / 1 | 5.5 | No |
47912 | CHEMBL391256 | C24H29N3O2 | 391.515 | 4 / 1 | 3.8 | Yes |
48189 | CHEMBL241212 | C24H29N3O2 | 391.515 | 4 / 1 | 3.8 | Yes |
49831 | CHEMBL1803049 | C28H39N5O3 | 493.652 | 7 / 0 | 4.6 | Yes |
50494 | CHEMBL1928124 | C27H39N3O4 | 469.626 | 6 / 1 | 3.4 | Yes |
51696 | CHEMBL378680 | C18H18Cl2N4 | 361.27 | 3 / 0 | 4.5 | Yes |
53507 | CHEMBL1928247 | C27H39N3O4 | 469.626 | 6 / 1 | 3.4 | Yes |
443899 | CHEMBL562591 | C18H19Cl2N5 | 376.285 | 4 / 0 | 4.2 | Yes |
56549 | CHEMBL272873 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
61842 | CHEMBL1765630 | C27H33ClN4O | 465.038 | 3 / 1 | 5.5 | No |
65392 | CHEMBL198993 | C21H27FN4O2 | 386.471 | 6 / 1 | 2.9 | Yes |
444276 | CHEMBL3318835 | C50H56Cl2F2N2O6 | 889.903 | 10 / 0 | 10.2 | No |
65731 | CHEMBL485227 | C26H36N2O | 392.587 | 2 / 1 | 6.3 | No |
66164 | CHEMBL574569 | C62H70N12O4 | 1047.32 | 12 / 2 | 8.8 | No |
444305 | CHEMBL3318845 | C23H25ClFNO3 | 417.905 | 5 / 0 | 3.8 | Yes |
66874 | CHEMBL1257811 | C23H28ClNO2 | 385.932 | 3 / 1 | 3.9 | Yes |
68622 | FAUC 213 | C18H19ClN4 | 326.828 | 3 / 0 | 3.2 | Yes |
71180 | CHEMBL1803030 | C26H35N5O3 | 465.598 | 7 / 0 | 3.7 | Yes |
72150 | CHEMBL391042 | C25H31N3O2 | 405.542 | 4 / 1 | 4.1 | Yes |
444668 | CHEMBL3318831 | C46H48Cl2F2N2O6 | 833.795 | 10 / 0 | 8.4 | No |
444684 | CHEMBL550920 | C20H25N5O | 351.454 | 5 / 0 | 3.3 | Yes |
76902 | CHEMBL573792 | C23H25Cl2N7O3 | 518.399 | 7 / 1 | 4.4 | No |
77830 | CHEMBL195247 | C20H24Cl2FN3O2S | 460.389 | 6 / 1 | 4.6 | Yes |
80456 | CHEMBL256492 | C21H27FN2O3 | 374.456 | 6 / 0 | 3.6 | Yes |
80735 | CHEMBL1928131 | C60H88N6O13 | 1101.39 | 17 / 2 | 4.4 | No |
80856 | CHEMBL240106 | C17H23BrN2O3 | 383.286 | 4 / 1 | 3.1 | Yes |
81396 | CHEMBL2443010 | C18H26FN5O2 | 363.437 | 7 / 0 | 1.3 | Yes |
82398 | CHEMBL1258036 | C30H33FN2O | 456.605 | 4 / 0 | 6.1 | No |
83258 | CHEMBL241438 | C31H35N3O2 | 481.64 | 4 / 1 | 5.9 | No |
87001 | CHEMBL270408 | C20H25FN2O2 | 344.43 | 5 / 0 | 3.6 | Yes |
87066 | QUINPIROLE | C13H21N3 | 219.332 | 2 / 1 | 2.3 | Yes |
91499 | CHEMBL405260 | C20H23FN4O | 354.429 | 5 / 0 | 2.8 | Yes |
445410 | CHEMBL549575 | C18H20ClN5 | 341.843 | 4 / 0 | 3.6 | Yes |
93546 | CHEMBL407818 | C18H20N4O | 308.385 | 4 / 1 | 2.1 | Yes |
95126 | CHEMBL198174 | C14H23N3O | 249.358 | 3 / 0 | 1.9 | Yes |
96273 | CHEMBL377542 | C17H18FN5 | 311.364 | 5 / 0 | 2.3 | Yes |
97845 | CHEMBL1928120 | C26H37N3O4 | 455.599 | 6 / 1 | 3.7 | Yes |
98176 | CHEMBL241424 | C30H33N3O2 | 467.613 | 4 / 1 | 5.5 | No |
101428 | CHEMBL484202 | C29H34N4 | 438.619 | 3 / 0 | 5.9 | No |
101537 | UNII-UGT5535REQ | C17H18ClNO | 287.787 | 2 / 1 | 4.0 | Yes |
445731 | CHEMBL562125 | C19H21Cl2N5 | 390.312 | 4 / 0 | 4.6 | Yes |
445770 | CHEMBL562064 | C20H25N5O | 351.454 | 5 / 0 | 3.3 | Yes |
104570 | CHEMBL378515 | C18H20ClN5O | 357.842 | 5 / 0 | 2.7 | Yes |
105784 | CHEMBL1258999 | C22H24FN3O2 | 381.451 | 5 / 1 | 2.9 | Yes |
445880 | HALOPERIDOL DECANOATE | C31H41ClFNO3 | 530.121 | 5 / 0 | 7.9 | No |
106709 | CHEMBL2443007 | C25H32FN5O3 | 469.561 | 8 / 0 | 3.3 | Yes |
111033 | CHEMBL182652 | C20H26IN3O2S | 499.411 | 5 / 1 | 4.2 | Yes |
113615 | CHEMBL1928121 | C50H68N6O9 | 897.127 | 13 / 2 | 5.6 | No |
114441 | CHEMBL194727 | C22H28FN3O2 | 385.483 | 5 / 1 | 3.6 | Yes |
115693 | CHEMBL1258382 | C33H37N3OS | 523.739 | 4 / 1 | 7.4 | No |
117373 | CHEMBL2397478 | C32H47N5O3 | 549.76 | 6 / 1 | 6.0 | No |
117375 | CHEMBL2397477 | C32H47N5O3 | 549.76 | 6 / 1 | 6.0 | No |
118723 | CHEMBL1928123 | C26H37N3O4 | 455.599 | 6 / 1 | 3.0 | Yes |
119243 | CHEMBL2207632 | C24H24N2O | 356.469 | 3 / 0 | 4.6 | Yes |
120525 | CHEMBL1916550 | C64H90N12O8 | 1155.5 | 16 / 2 | 9.3 | No |
122080 | CHEMBL2207637 | C25H31N3O | 389.543 | 4 / 0 | 4.1 | Yes |
124933 | CHEMBL2207641 | C34H40N4O2 | 536.72 | 6 / 0 | 5.7 | No |
126076 | CHEMBL484204 | C23H32N2O | 352.522 | 2 / 1 | 5.0 | Yes |
128139 | CHEMBL197195 | C20H23Cl2FN4O | 425.329 | 5 / 1 | 4.5 | Yes |
130490 | CHEMBL241211 | C27H25Cl2N3O | 478.417 | 3 / 1 | 6.1 | No |
130542 | CHEMBL2397392 | C23H30N4O | 378.52 | 3 / 1 | 3.4 | Yes |
130544 | CHEMBL2397476 | C23H30N4O | 378.52 | 3 / 1 | 3.4 | Yes |
134924 | CHEMBL1256169 | C41H45NO2 | 583.816 | 3 / 1 | 8.1 | No |
137700 | CHEMBL272073 | C19H22ClFN2O | 348.846 | 4 / 0 | 4.3 | Yes |
137873 | CHEMBL2207638 | C28H35N3O | 429.608 | 4 / 0 | 5.0 | Yes |
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