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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Sus scrofa (Pig)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	P50130
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5067
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	HALOPERIDOL DECANOATE
Molecular formula	C31H41ClFNO3
IUPAC name	[4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate
Molecular weight	530.121
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.9
Synonyms	AC1L1DVL CHEMBL1200986 EINECS 277-679-7 Haloperidol decanoate (JAN/USAN) KS-1419 SCHEMBL120575 API0024496 DECANOIC ACID 4-(4-CHLOROPHENYL)-1-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-4-PIPERIDINYL ESTER Haldol decanoas Haloperidol decanoate [USAN:USP:BAN:JAN] R 13,672 ZINC8214574 74050-97-8 CHEBI:31664 Depot haloperidol Halomonth (TN) KD 16 R-13,672 AC20PJ4101 CTK5D9276 FT-0669103 Haloperidol Decanoate HCl LS-59345 UNII-AC20PJ4101 4-(4-Chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidyl decanoate BDBM50053408 Decanoic acid, 4-(4-chlorophenyl)-1-(4-(4-fluorophenyl)-4-oxobutyl)-4-piperidinyl ester Haldol decanoate Haloperidol depot R 13672 [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate 77129-05-6 DTXSID50224951 KD-136 R-13672 AKOS025392169 D01898 Haldol Dec Haloperidol decanoate [USAN:BAN:JAN] MolPort-006-137-967 W0040 C31H41ClFNO3 Decanoic acid, ester with 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone Halomonth KD 136 R 13762 [ Show all ]
Inchi Key	GUTXTARXLVFHDK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H41ClFNO3/c1-2-3-4-5-6-7-8-11-30(36)37-31(26-14-16-27(32)17-15-26)20-23-34(24-21-31)22-9-10-29(35)25-12-18-28(33)19-13-25/h12-19H,2-11,20-24H2,1H3
PubChem CID	52919
ChEMBL	CHEMBL1200986
IUPHAR	N/A
BindingDB	50053408
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	140.0 nM	PMID25047579	BindingDB,ChEMBL

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