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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1258999
Molecular formula	C22H24FN3O2
IUPAC name	1-benzofuran-3-yl-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Molecular weight	381.451
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	benzofuran-3-yl(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone SCHEMBL3979504 BDBM50328638
Inchi Key	GUOJBWOHCJIFQW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24FN3O2/c1-16-6-7-17(25-12-16)13-24-15-22(23)8-10-26(11-9-22)21(27)19-14-28-20-5-3-2-4-18(19)20/h2-7,12,14,24H,8-11,13,15H2,1H3
PubChem CID	42606573
ChEMBL	CHEMBL1258999
IUPHAR	N/A
BindingDB	50328638
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
105783	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
105786	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
105784	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
105782	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
105785	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
524593	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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