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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL377542
Molecular formula	C17H18FN5
IUPAC name	2-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyrazine
Molecular weight	311.364
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	2.3
Synonyms	2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrazine BDBM50189838
Inchi Key	GHAOYUDOVIKTMJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18FN5/c18-14-1-3-16(4-2-14)22-9-7-21(8-10-22)12-15-13-23-6-5-19-11-17(23)20-15/h1-6,11,13H,7-10,12H2
PubChem CID	11659604
ChEMBL	CHEMBL377542
IUPHAR	N/A
BindingDB	50189838
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
96273	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
96274	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
96272	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
96275	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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