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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	fauc-365
Molecular formula	C23H25Cl2N3OS
IUPAC name	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-benzothiophene-2-carboxamide
Molecular weight	462.433
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.2
Synonyms	AS-16480 MolPort-039-138-738 C23H25Cl2N3OS SYN5116 BDBM50119390 N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)benzo[b]thiophene-2-carboxamide ZINC13491634 AOB1711 KB-272558 Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide NCGC00370702-02 474432-66-1 CHEMBL59725 [ Show all ]
Inchi Key	CPTSTFKVXWZGEV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25Cl2N3OS/c24-18-7-5-8-19(22(18)25)28-14-12-27(13-15-28)11-4-3-10-26-23(29)21-16-17-6-1-2-9-20(17)30-21/h1-2,5-9,16H,3-4,10-15H2,(H,26,29)
PubChem CID	10276451
ChEMBL	CHEMBL59725
IUPHAR	N/A
BindingDB	50119390
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
47676	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
468794	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
47675	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
47680	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
47678	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
47679	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
47673	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
47674	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
47677	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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