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| Name | D(3) dopamine receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Drd3 |
| Synonym | D3 receptor D3R Dopamine D3 receptor dopaminergic receptor D3 |
| Disease | N/A for non-human GPCRs |
| Length | 446 |
| Amino acid sequence | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC |
| UniProt | P19020 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3138 |
| IUPHAR | 216 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 555476 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 625 |  CHEMBL306197 | C25H32N2O | 376.544 | 2 / 1 | 6.0 | No |
| 745 |  CHEMBL367875 | C21H27N3OS | 369.527 | 4 / 0 | 3.4 | Yes |
| 1455 |  CHEMBL457025 | C25H35N3O | 393.575 | 4 / 1 | 4.8 | Yes |
| 1458 |  CHEMBL457024 | C25H35N3O | 393.575 | 4 / 1 | 4.8 | Yes |
| 3348 |  CHEMBL92713 | C21H26ClN3O2 | 387.908 | 4 / 1 | 3.8 | Yes |
| 3593 |  tranylcypromine | C9H11N | 133.194 | 1 / 1 | 1.5 | Yes |
| 4442 |  CHEMBL298759 | C21H25BrN2O2 | 417.347 | 3 / 1 | 4.6 | Yes |
| 4445 |  CHEMBL50517 | C21H25BrN2O2 | 417.347 | 3 / 1 | 4.6 | Yes |
| 521607 |  CHEMBL3764191 | C21H23F3N4OS2 | 468.557 | 9 / 0 | 4.0 | Yes |
| 5418 |  CHEMBL413554 | C20H21FN2O | 324.399 | 4 / 0 | 3.8 | Yes |
| 5455 |  CHEMBL175226 | C19H24ClN3OS | 377.931 | 4 / 0 | 2.8 | Yes |
| 5710 |  CHEMBL468022 | C24H37N5S | 427.655 | 6 / 1 | 4.7 | Yes |
| 6881 |  CHEMBL171519 | C14H15N3 | 225.295 | 2 / 2 | 1.5 | Yes |
| 7869 |  CHEMBL173658 | C15H16N4 | 252.321 | 4 / 2 | 1.1 | Yes |
| 8791 |  CHEMBL262794 | C19H19N3O2S | 353.44 | 5 / 0 | 2.4 | Yes |
| 10028 |  CHEMBL450863 | C16H23NO | 245.366 | 2 / 1 | 3.5 | Yes |
| 11339 |  CHEMBL93198 | C22H26ClN3O3 | 415.918 | 4 / 2 | 3.2 | Yes |
| 11735 |  propranolol | C16H21NO2 | 259.349 | 3 / 2 | 3.0 | Yes |
| 12015 |  CHEMBL1253769 | C30H38N4O | 470.661 | 5 / 1 | 5.4 | No |
| 13672 |  8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 14726 |  CHEMBL315879 | C22H28ClN3O2 | 401.935 | 4 / 1 | 4.1 | Yes |
| 14777 |  CHEMBL1221545 | C25H31N3O3S | 453.601 | 6 / 1 | 4.5 | Yes |
| 14905 |  CHEMBL193620 | C21H26F3N3O2 | 409.453 | 7 / 0 | 3.1 | Yes |
| 15968 |  CHEMBL468833 | C22H27Cl2N5S | 464.453 | 6 / 1 | 4.4 | Yes |
| 555552 |  Pipamperone | C21H30FN3O2 | 375.488 | 5 / 1 | 2.0 | Yes |
| 17114 |  SCHEMBL977787 | C22H35Cl2N7O2 | 500.469 | 7 / 2 | 3.2 | No |
| 17187 |  CHEMBL303021 | C18H25ClN2 | 304.862 | 1 / 1 | 5.2 | No |
| 17892 |  Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
| 18218 |  CHEMBL139081 | C20H20BrNS | 386.351 | 2 / 0 | 5.8 | No |
| 18462 |  CHEMBL157322 | C20H24ClN3O2 | 373.881 | 4 / 1 | 3.4 | Yes |
| 18718 |  CHEMBL361299 | C15H19N | 213.324 | 1 / 0 | 2.3 | Yes |
| 18925 |  CHEMBL118636 | C16H23N3S | 289.441 | 4 / 1 | 4.2 | Yes |
| 19704 |  CHEMBL181203 | C28H31N3O | 425.576 | 3 / 1 | 5.3 | No |
| 21197 |  CHEMBL465696 | C29H24ClNO3 | 469.965 | 4 / 3 | N/A | N/A |
| 21212 |  CHEMBL514411 | C25H33N3O | 391.559 | 4 / 1 | 4.3 | Yes |
| 21232 |  (RS)-PPCC | C24H29NO3 | 379.5 | 4 / 1 | 3.5 | Yes |
| 22059 |  CHEMBL1254862 | C30H38N4O | 470.661 | 5 / 1 | 5.4 | No |
| 22093 |  CHEMBL549968 | C28H35N3O3 | 461.606 | 5 / 1 | 4.9 | Yes |
| 22557 |  CHEMBL283036 | C19H19F3N4 | 360.384 | 6 / 1 | 3.6 | Yes |
| 22848 |  CHEMBL143509 | C21H28N2O2 | 340.467 | 4 / 0 | 4.0 | Yes |
| 23244 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 555566 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 553364 |  (+)-sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 555570 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 23588 |  CHEMBL2387636 | C32H40N4O | 496.699 | 4 / 1 | 6.0 | No |
| 25148 |  CHEMBL340641 | C24H26Cl2N4O | 457.399 | 4 / 1 | 5.3 | No |
| 522367 |  CHEMBL3764739 | C22H26F3N5OS | 465.539 | 8 / 0 | 3.1 | Yes |
| 26587 |  Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
| 26801 |  CHEMBL69562 | C19H28N2 | 284.447 | 1 / 1 | 5.0 | Yes |
| 27125 |  7-OH-DPAT | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
| 28456 |  CHEMBL362060 | C18H19N3OS | 325.43 | 4 / 0 | 2.7 | Yes |
| 29105 |  CHEMBL52300 | C24H31BrN2O2 | 459.428 | 3 / 1 | 6.1 | No |
| 29106 |  CHEMBL301732 | C24H31BrN2O2 | 459.428 | 3 / 1 | 6.1 | No |
| 29742 |  CHEMBL96792 | C16H20ClN3O3 | 337.804 | 4 / 3 | 1.2 | Yes |
| 30936 |  CHEMBL141614 | C19H27N3O2S | 361.504 | 6 / 1 | 3.8 | Yes |
| 31517 |  CHEMBL458587 | C25H26N2O2 | 386.495 | 4 / 2 | 4.0 | Yes |
| 33388 |  CHEMBL420510 | C26H32N4O2 | 432.568 | 4 / 0 | 3.8 | Yes |
| 555611 |  Clebopride | C20H24ClN3O2 | 373.881 | 4 / 2 | 3.2 | Yes |
| 34782 |  CHEMBL71091 | C18H26N2O | 286.419 | 2 / 1 | 3.3 | Yes |
| 34813 |  CHEMBL160817 | C23H27N3O3 | 393.487 | 6 / 1 | 4.6 | Yes |
| 443105 |  CHEMBL3393789 | C31H35ClFNO3 | 524.073 | 5 / 1 | 6.5 | No |
| 443107 |  CHEMBL3393790 | C31H35ClFNO3 | 524.073 | 5 / 1 | 6.5 | No |
| 35752 |  CHEMBL1649601 | C31H35ClFNO3 | 524.073 | 5 / 1 | 6.5 | No |
| 39192 |  CHEMBL127317 | C25H30N4O2 | 418.541 | 5 / 1 | 4.1 | Yes |
| 39439 |  Centpyraquin | C22H25FN2O | 352.453 | 4 / 0 | 4.1 | Yes |
| 40317 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 41663 |  2-Dipropylamino-indan-5-ol | C15H23NO | 233.355 | 2 / 1 | 3.8 | Yes |
| 42297 |  CHEMBL2112317 | C27H39N3O4 | 469.626 | 5 / 2 | N/A | N/A |
| 42568 |  CHEMBL2206273 | C33H50N2O2 | 506.775 | 4 / 2 | 8.2 | No |
| 43446 |  CHEMBL85362 | C15H23NO | 233.355 | 2 / 1 | 3.8 | Yes |
| 43569 |  CHEMBL54667 | C23H29BrN2O2 | 445.401 | 3 / 1 | 5.7 | No |
| 43572 |  CHEMBL53320 | C23H29BrN2O2 | 445.401 | 3 / 1 | 5.7 | No |
| 44110 |  CHEMBL64260 | C22H28N2O4 | 384.476 | 5 / 1 | 3.0 | Yes |
| 46948 |  CHEMBL561511 | C29H36N4O2 | 472.633 | 5 / 1 | 4.5 | Yes |
| 555660 |  Dinapsoline,(+/-)-N-allyl | C19H19NO2 | 293.366 | 3 / 2 | 3.2 | Yes |
| 47673 |  fauc-365 | C23H25Cl2N3OS | 462.433 | 4 / 1 | 6.2 | No |
| 47744 |  CHEMBL328866 | C23H26ClN3O3 | 427.929 | 4 / 2 | 3.2 | Yes |
| 47751 |  CHEMBL319079 | C23H26ClN3O3 | 427.929 | 4 / 2 | 3.2 | Yes |
| 47765 |  CHEMBL2152747 | C25H34N6OS | 466.648 | 6 / 2 | 3.8 | Yes |
| 47767 |  CHEMBL2152748 | C25H34N6OS | 466.648 | 6 / 2 | 3.8 | Yes |
| 47769 |  CHEMBL2152746 | C25H34N6OS | 466.648 | 6 / 2 | 3.8 | Yes |
| 48045 |  CHEMBL152756 | C26H31N3O2 | 417.553 | 4 / 1 | 4.8 | Yes |
| 522958 |  CHEMBL3765266 | C26H27F3N6O2S | 544.597 | 11 / 0 | 4.6 | No |
| 48685 |  CHEMBL2112905 | C20H28Cl2N4O2 | 427.37 | 5 / 3 | N/A | N/A |
| 50086 |  CHEMBL186350 | C21H23N | 289.422 | 1 / 0 | 3.9 | Yes |
| 51514 |  CHEMBL309118 | C27H25Cl2N3O2 | 494.416 | 4 / 1 | 5.6 | No |
| 52892 |  CHEMBL124918 | C19H23N | 265.4 | 1 / 0 | 4.7 | Yes |
| 52893 |  CHEMBL338253 | C19H23N | 265.4 | 1 / 0 | 4.7 | Yes |
| 53386 |  CHEMBL299691 | C21H28FN3O2 | 373.472 | 5 / 0 | 2.9 | Yes |
| 53693 |  CHEMBL339960 | C23H26Cl2N4O | 445.388 | 3 / 2 | 5.3 | No |
| 54130 |  CHEMBL161921 | C15H20N2 | 228.339 | 2 / 1 | 3.2 | Yes |
| 55661 |  CHEMBL304984 | C19H24N2O | 296.414 | 2 / 1 | 3.8 | Yes |
| 523153 |  CHEMBL3740778 | C25H29ClF3N7O2S | 584.059 | 12 / 3 | N/A | No |
| 443932 |  CHEMBL142688 | C19H27NO2 | 301.43 | 3 / 0 | 3.8 | Yes |
| 57132 |  CHEMBL126770 | C19H24N+ | 266.408 | 0 / 0 | 4.1 | Yes |
| 57707 |  CHEMBL3125993 | C30H41N5OS | 519.752 | 7 / 2 | 5.9 | No |
| 58321 |  CHEMBL1254946 | C25H34IN3O | 519.471 | 4 / 1 | 5.5 | No |
| 60179 |  CHEMBL71865 | C21H23Cl2N3O | 404.335 | 3 / 1 | 4.4 | Yes |
| 60184 |  CHEMBL71327 | C21H23Cl2N3O | 404.335 | 3 / 1 | 4.4 | Yes |
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