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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL340641
Molecular formula	C24H26Cl2N4O
IUPAC name	N-[4-[4-(2,4-dichlorophenyl)piperazin-1-yl]butyl]isoquinoline-3-carboxamide
Molecular weight	457.399
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50131921 Isoquinoline-3-carboxylic acid {4-[4-(2,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Inchi Key	BJILZOKLMRTDFN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26Cl2N4O/c25-20-7-8-23(21(26)16-20)30-13-11-29(12-14-30)10-4-3-9-27-24(31)22-15-18-5-1-2-6-19(18)17-28-22/h1-2,5-8,15-17H,3-4,9-14H2,(H,27,31)
PubChem CID	11091738
ChEMBL	CHEMBL340641
IUPHAR	N/A
BindingDB	50131921
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25147	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
25149	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
25150	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
25146	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
25151	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
25148	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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