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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(3) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd3
Synonym	D3 receptor D3R Dopamine D3 receptor dopaminergic receptor D3
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
UniProt	P19020
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3138
IUPHAR	216
DrugBank	N/A

Ligand

Name	CHEMBL186350
Molecular formula	C21H23N
IUPAC name	3-(2-phenylethyl)-2,4,5,6-tetrahydro-1H-benzo[f]isoquinoline
Molecular weight	289.422
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	3.9
Synonyms	AC1MCDNU 3-phenethyl-2,4,5,6-tetrahydro-1H-benzo[f]isoquinoline ZINC4040585 BDBM50155605 1,2,3,4,5,6-Hexahydro-3-(2-phenylethyl)benz[f]isoquinoline Oprea1_850437 3-Phenethyl-1,2,3,4,5,6-hexahydro-benzo[f]isoquinoline SCHEMBL7530169 [ Show all ]
Inchi Key	CTGJCBHUIMTVHX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23N/c1-2-6-17(7-3-1)12-14-22-15-13-21-19(16-22)11-10-18-8-4-5-9-20(18)21/h1-9H,10-16H2
PubChem CID	2767081
ChEMBL	CHEMBL186350
IUPHAR	N/A
BindingDB	50155605
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	84.0 nM	PMID15501046	BindingDB,ChEMBL

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