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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL420510
Molecular formula	C26H32N4O2
IUPAC name	2-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-3,4-dihydropyrazino[1,2-a]indol-1-one
Molecular weight	432.568
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.8
Synonyms	BDBM50131920 SCHEMBL4525982 2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one
Inchi Key	BUVJSGDYMDZIDN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H32N4O2/c1-32-25-11-5-4-10-23(25)28-16-14-27(15-17-28)12-6-7-13-29-18-19-30-22-9-3-2-8-21(22)20-24(30)26(29)31/h2-5,8-11,20H,6-7,12-19H2,1H3
PubChem CID	11732785
ChEMBL	CHEMBL420510
IUPHAR	N/A
BindingDB	50131920
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33389	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
33392	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
33391	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
33390	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
33387	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
33388	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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