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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(RS)-PPCC
Molecular formula	C24H29NO3
IUPAC name	methyl 2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropane-1-carboxylate
Molecular weight	379.5
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.5
Synonyms	GTPL6676 BDBM50206578 SCHEMBL18261107 cis-((+/-)-Methyl(1R,2S/1S,2R)-2-[(4-Hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)-methyl]-1-(4-methylphenyl)cyclopropanecarboxylate D07LVT methyl 2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropane-1-carboxylate CHEMBL222301 [ Show all ]
Inchi Key	BDSYECBSUUOPCT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29NO3/c1-18-8-10-20(11-9-18)24(22(26)28-2)16-21(24)17-25-14-12-23(27,13-15-25)19-6-4-3-5-7-19/h3-11,21,27H,12-17H2,1-2H3
PubChem CID	16726095
ChEMBL	CHEMBL222301
IUPHAR	N/A
BindingDB	50206578
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21231	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
21235	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
21229	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
21234	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
21233	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
21228	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
21232	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
21230	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486

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