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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3764191
Molecular formula	C21H23F3N4OS2
IUPAC name	4-[3-[(4-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]morpholine
Molecular weight	468.557
Hydrogen bond acceptor	9
Hydrogen bond donor	0
XlogP	4.0
Synonyms	BDBM50139866 SCHEMBL18741893
Inchi Key	AGPVWRLINFFKSF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H23F3N4OS2/c1-27-19(16-7-12-30-14-16)25-26-20(27)31-11-2-8-28-9-10-29-18(13-28)15-3-5-17(6-4-15)21(22,23)24/h3-7,12,14,18H,2,8-11,13H2,1H3
PubChem CID	127041673
ChEMBL	CHEMBL3764191
IUPHAR	N/A
BindingDB	50139866
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521609	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
521607	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
521608	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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