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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL457024
Molecular formula	C25H35N3O
IUPAC name	(6S)-6-[2-(4-phenylpiperazin-1-yl)ethyl-propylamino]-5,6,7,8-tetrahydronaphthalen-1-ol
Molecular weight	393.575
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	(S)-6-[Propyl[2-(4-phenylpiperazino)ethyl]amino]-5,6,7,8-tetrahydronaphthalene-1-ol (-)-(S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol SCHEMBL10075561 (S)-6-((2-(4-phenylpiperazin-1-yl)ethyl)(propyl)amino)-5,6,7,8-tetrahydronaphthalen-1-ol BDBM50273938 D0FU2V [ Show all ]
Inchi Key	ACDYFMOSSUKHJD-QHCPKHFHSA-N
Inchi ID	InChI=1S/C25H35N3O/c1-2-13-27(23-11-12-24-21(20-23)7-6-10-25(24)29)17-14-26-15-18-28(19-16-26)22-8-4-3-5-9-22/h3-10,23,29H,2,11-20H2,1H3/t23-/m0/s1
PubChem CID	24754542
ChEMBL	CHEMBL457024
IUPHAR	N/A
BindingDB	50273938
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1456	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
535950	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
1457	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
1458	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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