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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL175226
Molecular formula	C19H24ClN3OS
IUPAC name	8-chloro-3-(methoxymethyl)-6-(4-methylpiperazin-1-yl)-5,6-dihydropyrrolo[2,1-b][1,3]benzothiazepine
Molecular weight	377.931
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	2.8
Synonyms	BDBM50137979 7-Chloro-1-methoxymethyl-9-(4-methyl-piperazin-1-yl)-9,10-dihydro-4-thia-10a-aza-benzo[f]azulene
Inchi Key	AHDOWCJMWQLFRW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24ClN3OS/c1-21-7-9-22(10-8-21)17-12-23-15(13-24-2)4-6-19(23)25-18-5-3-14(20)11-16(17)18/h3-6,11,17H,7-10,12-13H2,1-2H3
PubChem CID	11406281
ChEMBL	CHEMBL175226
IUPHAR	N/A
BindingDB	50137979
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5452	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
5454	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
5453	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
5455	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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