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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL127317
Molecular formula	C25H30N4O2
IUPAC name	N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]quinoline-2-carboxamide
Molecular weight	418.541
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	Quinoline-2-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide BDBM50131934 N-(4-(4-(2-Methoxyphenyl)-1-piperazinyl)butyl)quinoline-2-carboxamide
Inchi Key	CDDVHWKFFCJTOZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30N4O2/c1-31-24-11-5-4-10-23(24)29-18-16-28(17-19-29)15-7-6-14-26-25(30)22-13-12-20-8-2-3-9-21(20)27-22/h2-5,8-13H,6-7,14-19H2,1H3,(H,26,30)
PubChem CID	10862670
ChEMBL	CHEMBL127317
IUPHAR	N/A
BindingDB	50131934
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39193	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
39190	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
39191	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
39192	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
39194	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400

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