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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL977787
Molecular formula	C22H35Cl2N7O2
IUPAC name	N-[4-[2-[4-[5,6-dichloro-2-(methylamino)pyrimidin-4-yl]piperazin-1-yl]ethyl]cyclohexyl]morpholine-4-carboxamide
Molecular weight	500.469
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	3.2
Synonyms	BDBM129719 US8802672, 7 CHEMBL3701896
Inchi Key	AXVHZOULLRVZMO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H35Cl2N7O2/c1-25-21-27-19(24)18(23)20(28-21)30-10-8-29(9-11-30)7-6-16-2-4-17(5-3-16)26-22(32)31-12-14-33-15-13-31/h16-17H,2-15H2,1H3,(H,26,32)(H,25,27,28)
PubChem CID	25052021
ChEMBL	CHEMBL3701896
IUPHAR	N/A
BindingDB	129719
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17112	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
17113	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
17114	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446

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