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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	DIHYDREXIDINE
Molecular formula	C17H17NO2
IUPAC name	(6aR,12bS)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol
Molecular weight	267.328
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.5
Synonyms	IP-202 trans-10,11-dihydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol CCG-204474 CHEMBL25856 NCGC00015354-01 ZINC25758512 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol BDBM50010686 Dihydrexidine hydrochloride Rel-Dihydrexidine 10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX) Biomol-NT_000033 Lopac-D-5814 UNII-32D64VH037 component BGOQGUHWXBGXJW-RHSMWYFYSA-N (+)-Dihydrexidine CHEBI:124993 DAR-0100 NCGC00024845-04 (6aR,12bS)-5,6,6a,7,8,12b-Hexahydrobenzo(a)phenanthridine-10,11-diol Benzo(a)phenanthridine-10,11-diol, 5,6,6a,7,8,12b-hexahydro-, (6aR,12bS)- Dihydrexidine, (+)- SCHEMBL4614575 174691-84-0 BPBio1_001227 Lopac0_000380 UNII-Q3PJ4B4D0X (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium AC1O7G2G Q3PJ4B4D0X (6aR,12bS)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol Benzo(a)phenanthridine-10,11-diol, 5,6,6a,7,8,12b-hexahydro-, (6ar-trans)- [ Show all ]
Inchi Key	BGOQGUHWXBGXJW-RHSMWYFYSA-N
Inchi ID	InChI=1S/C17H17NO2/c19-15-7-10-5-6-14-17(13(10)8-16(15)20)12-4-2-1-3-11(12)9-18-14/h1-4,7-8,14,17-20H,5-6,9H2/t14-,17-/m1/s1
PubChem CID	6603820
ChEMBL	CHEMBL25856
IUPHAR	N/A
BindingDB	50010686
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23245	5-hydroxytryptamine receptor 1A	Q64264	Htr1a	Mus musculus (Mouse)	421
23243	5-hydroxytryptamine receptor 2A	Q75Z89	HTR2A	Bos taurus (Bovine)	470
23248	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
23239	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
23240	Alpha-2A adrenergic receptor	P22909	Adra2a	Rattus norvegicus (Rat)	450
23233	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
23236	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
23241	D(1) dopamine receptor	P35406		Carassius auratus (Goldfish)	363
23231	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
23237	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
23242	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
23247	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
23232	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
23234	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
23244	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
23235	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
23238	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
23246	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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