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| Name | D(4) dopamine receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Drd4 |
| Synonym | D(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4 |
| Disease | N/A for non-human GPCRs |
| Length | 387 |
| Amino acid sequence | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC |
| UniProt | P30729 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL3361 |
| IUPHAR | 217 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 86 |  Eticlopride | C17H25ClN2O3 | 340.848 | 4 / 2 | 3.1 | Yes |
| 521455 |  CHEMBL3818128 | C19H23ClFN | 319.848 | 2 / 1 | N/A | N/A |
| 3144 |  AC1N0YGA | C3H7NO4S | 153.152 | 5 / 2 | -4.7 | Yes |
| 10876 |  CHEMBL3289645 | C19H22F3N3O | 365.4 | 7 / 0 | 4.0 | Yes |
| 12834 |  CHEMBL1940408 | C20H24ClFN2 | 346.874 | 3 / 0 | 5.3 | No |
| 16078 |  CHEMBL1946122 | C22H25ClFNO2 | 389.895 | 4 / 1 | 4.8 | Yes |
| 442287 |  CHEMBL3321789 | C22H25ClFNO2 | 389.895 | 4 / 1 | 4.8 | Yes |
| 548086 |  CHEMBL3952251 | C20H23Cl2NO | 364.31 | 2 / 1 | N/A | N/A |
| 20014 |  CHEMBL1270227 | C19H21ClFN3O | 361.845 | 4 / 1 | 3.6 | Yes |
| 22549 |  CHEMBL283036 | C19H19F3N4 | 360.384 | 6 / 1 | 3.6 | Yes |
| 23235 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 23251 |  DIHYDREXIDINE | C17H17NO2 | 267.328 | 3 / 3 | 2.5 | Yes |
| 23345 |  Levosulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 23363 |  sulpiride | C15H23N3O4S | 341.426 | 6 / 2 | 0.6 | Yes |
| 29415 |  CHEMBL1940420 | C18H22FN3O | 315.392 | 5 / 0 | 3.7 | Yes |
| 29573 |  CHEMBL3289653 | C21H23ClN2O | 354.878 | 3 / 0 | 5.2 | No |
| 37776 |  CHEMBL219179 | C17H19N5O | 309.373 | 5 / 2 | 1.9 | Yes |
| 548339 |  CHEMBL3898250 | C20H21Cl2NO | 362.294 | 2 / 1 | N/A | N/A |
| 39438 |  Centpyraquin | C22H25FN2O | 352.453 | 4 / 0 | 4.1 | Yes |
| 40291 |  Aripiprazole | C23H27Cl2N3O2 | 448.388 | 4 / 1 | 4.6 | Yes |
| 41970 |  CHEMBL2037531 | C23H26N2OS | 378.534 | 4 / 0 | 5.3 | No |
| 548376 |  CHEMBL3959919 | C22H26Cl2N2O2S | 453.422 | 5 / 1 | N/A | N/A |
| 44308 |  CHEMBL1270013 | C21H24N4O3 | 380.448 | 6 / 1 | 2.9 | Yes |
| 47138 |  Dinapsoline,(+/-)-N-allyl | C19H19NO2 | 293.366 | 3 / 2 | 3.2 | Yes |
| 47274 |  CHEMBL3289643 | C21H23ClN2O | 354.878 | 3 / 0 | 4.3 | Yes |
| 548437 |  CHEMBL3978642 | C20H22ClNO | 327.852 | 2 / 1 | N/A | N/A |
| 522908 |  CHEMBL3819082 | C20H23ClFN | 331.859 | 2 / 1 | N/A | N/A |
| 548447 |  CHEMBL3890841 | C20H21N | 275.395 | 1 / 0 | 4.1 | Yes |
| 52549 |  CHEMBL2037520 | C24H25ClN4O2S | 469.0 | 5 / 1 | 4.8 | Yes |
| 52794 |  CHEMBL1940405 | C20H23ClFNS | 363.919 | 3 / 0 | 5.8 | No |
| 443822 |  CHEMBL210578 | C23H25ClFNO2 | 401.906 | 4 / 1 | 4.4 | Yes |
| 523081 |  CHEMBL3818669 | C20H20N2O2 | 320.392 | 3 / 0 | 3.3 | Yes |
| 54509 |  CHEMBL2037432 | C22H25ClN2OS | 400.965 | 4 / 1 | 5.2 | No |
| 58704 |  CHEMBL1940413 | C19H23ClN2O | 330.856 | 3 / 0 | 4.5 | Yes |
| 61887 |  CHEMBL1270423 | C19H20FN5O | 353.401 | 6 / 1 | 1.9 | Yes |
| 62229 |  spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
| 62414 |  MELPERONE | C16H22FNO | 263.356 | 3 / 0 | 3.3 | Yes |
| 553574 |  PD-168077 | C20H22N4O | 334.423 | 4 / 1 | 3.0 | Yes |
| 66656 |  N-(2-[4-(4-Chlorophenyl)piperazin-1-yl]ethyl)-3-methoxybenzamide | C20H24ClN3O2 | 373.881 | 4 / 1 | 3.4 | Yes |
| 68621 |  FAUC 213 | C18H19ClN4 | 326.828 | 3 / 0 | 3.2 | Yes |
| 70327 |  CHEMBL190821 | C31H38N4O2 | 498.671 | 5 / 1 | 5.1 | No |
| 70329 |  CHEMBL193300 | C31H38N4O2 | 498.671 | 5 / 1 | 5.1 | No |
| 71166 |  CHEMBL3289654 | C22H23ClN2O | 366.889 | 3 / 0 | 5.5 | No |
| 71943 |  CHEMBL2037529 | C20H23N5OS | 381.498 | 7 / 0 | 3.3 | Yes |
| 72909 |  CHEMBL371200 | C28H33N3O2 | 443.591 | 4 / 1 | 5.2 | No |
| 72913 |  CHEMBL434532 | C28H33N3O2 | 443.591 | 4 / 1 | 5.2 | No |
| 73177 |  CHEMBL1258452 | C18H28N2O3 | 320.433 | 5 / 1 | 3.1 | Yes |
| 76478 |  CHEMBL89738 | C17H22N2 | 254.377 | 1 / 1 | 3.4 | Yes |
| 76942 |  methionine zwitterion | C5H11NO2S | 149.208 | 3 / 1 | -1.2 | Yes |
| 77013 |  DL-Homocysteine | C4H9NO2S | 135.181 | 4 / 3 | -3.4 | Yes |
| 77729 |  CHEMBL1940417 | C17H21FN4O | 316.38 | 6 / 0 | 2.6 | Yes |
| 78060 |  CHEMBL1940403 | C20H23ClFNOS | 379.918 | 4 / 1 | 4.1 | Yes |
| 79052 |  CHEMBL3289383 | C19H22ClFN2OS | 380.906 | 5 / 0 | 3.7 | Yes |
| 80431 |  CHEMBL282829 | C20H24N4 | 320.44 | 3 / 1 | 3.5 | Yes |
| 81103 |  CHEMBL363406 | C28H33N3O2 | 443.591 | 4 / 1 | 5.2 | No |
| 81108 |  CHEMBL192439 | C28H33N3O2 | 443.591 | 4 / 1 | 5.2 | No |
| 81401 |  CHEMBL3289647 | C19H24FN3S | 345.48 | 5 / 0 | 4.1 | Yes |
| 523948 |  CHEMBL3819556 | C18H21ClFNS | 337.881 | 3 / 1 | N/A | N/A |
| 548869 |  CHEMBL3924565 | C20H23Cl2NO | 364.31 | 2 / 1 | N/A | N/A |
| 85596 |  ABT-724 | C17H19N5 | 293.374 | 4 / 1 | 2.2 | Yes |
| 88306 |  CHEMBL1946253 | C21H26ClFN2 | 360.901 | 3 / 0 | 5.6 | No |
| 548948 |  CHEMBL3890153 | C19H21BrN2S | 389.355 | 3 / 1 | N/A | N/A |
| 94899 |  thiothixene | C23H29N3O2S2 | 443.624 | 6 / 0 | 3.8 | Yes |
| 549073 |  CHEMBL3986927 | C21H22N2O2 | 334.419 | 3 / 1 | 2.3 | Yes |
| 102911 |  CHEMBL516641 | C35H52O4 | 536.797 | 4 / 0 | 10.0 | No |
| 104671 |  CHEMBL1940415 | C18H23FN4 | 314.408 | 5 / 0 | 3.2 | Yes |
| 105652 |  Remoxipride | C16H23BrN2O3 | 371.275 | 4 / 1 | 2.1 | Yes |
| 105798 |  BRN 4530212 | C19H23FN2O | 314.404 | 4 / 0 | 4.0 | Yes |
| 105803 |  CHEMBL1270120 | C21H24N4O2 | 364.449 | 5 / 1 | 2.5 | Yes |
| 109151 |  SERTINDOLE | C24H26ClFN4O | 440.947 | 3 / 1 | 4.1 | Yes |
| 112197 |  zotepine | C18H18ClNOS | 331.858 | 3 / 0 | 4.8 | Yes |
| 114641 |  CHEMBL29808 | C20H22N4 | 318.424 | 3 / 1 | 3.5 | Yes |
| 524923 |  CHEMBL3818047 | C19H20ClNO | 313.825 | 2 / 0 | 4.1 | Yes |
| 119214 |  CHEMBL28997 | C18H19FN4 | 310.376 | 4 / 1 | 2.8 | Yes |
| 524995 |  CHEMBL3819427 | C20H22N2O2 | 322.408 | 3 / 1 | 2.3 | Yes |
| 549472 |  CHEMBL3908870 | C19H26N2O2 | 314.429 | 3 / 0 | 2.2 | Yes |
| 128526 |  CHEMBL2037518 | C22H24N2OS | 364.507 | 4 / 0 | 5.0 | Yes |
| 128763 |  CHEMBL82591 | C22H28N2O2 | 352.478 | 4 / 0 | 3.6 | Yes |
| 128770 |  CHEMBL309730 | C22H28N2O2 | 352.478 | 4 / 0 | 3.6 | Yes |
| 128778 |  CHEMBL71724 | C22H28N2O2 | 352.478 | 4 / 0 | 3.6 | Yes |
| 130289 |  CHEMBL435949 | C19H22N4O | 322.412 | 4 / 1 | 2.7 | Yes |
| 553943 |  Nafadotride | C22H27N3O2 | 365.477 | 4 / 1 | 4.0 | Yes |
| 131484 |  CHEMBL1940419 | C18H22FN3S | 331.453 | 5 / 0 | 4.2 | Yes |
| 525345 |  CHEMBL3819366 | C18H21ClFNO | 321.82 | 3 / 1 | N/A | N/A |
| 140881 |  CHEMBL1270323 | C20H21FN4O2 | 368.412 | 6 / 1 | 3.0 | Yes |
| 141456 |  CHEMBL2037519 | C19H21N5OS | 367.471 | 7 / 0 | 2.9 | Yes |
| 554017 |  630116-49-3 | C19H23N3O | 309.413 | 3 / 1 | 3.3 | Yes |
| 151603 |  CHEMBL345820 | C26H29Cl2N3O2 | 486.437 | 4 / 1 | 6.0 | No |
| 153992 |  CHEMBL3289642 | C21H22ClFN2O | 372.868 | 4 / 0 | 4.4 | Yes |
| 156888 |  CHEMBL1940404 | C20H23ClFNO2 | 363.857 | 4 / 1 | 3.6 | Yes |
| 525986 |  CHEMBL3818200 | C20H20N2O | 304.393 | 3 / 0 | 3.2 | Yes |
| 526210 |  CHEMBL3818989 | C19H21NO | 279.383 | 2 / 0 | 3.5 | Yes |
| 167350 |  CHEMBL3289648 | C20H26FN3 | 327.447 | 4 / 0 | 4.3 | Yes |
| 168760 |  AC1L5523 | C19H19ClN2 | 310.825 | 2 / 0 | 4.2 | Yes |
| 168978 |  CHEMBL287671 | C24H24N4 | 368.484 | 3 / 1 | 4.4 | Yes |
| 170116 |  CHEMBL191815 | C27H31N3O | 413.565 | 3 / 1 | 5.3 | No |
| 170121 |  CHEMBL179757 | C27H31N3O | 413.565 | 3 / 1 | 5.3 | No |
| 170124 |  CHEMBL427173 | C27H31N3O | 413.565 | 3 / 1 | 5.3 | No |
| 170156 |  D-HOMOCYSTEINE THIOLACTONE | C4H7NOS | 117.166 | 3 / 1 | -0.1 | Yes |
| 170207 |  Homocysteine thiolactone | C4H7NOS | 117.166 | 3 / 1 | -0.1 | Yes |
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