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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2037432
Molecular formula	C22H25ClN2OS
IUPAC name	1-[4-(1,3-benzothiazol-2-yl)butyl]-4-(4-chlorophenyl)piperidin-4-ol
Molecular weight	400.965
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50384970
Inchi Key	CZOXEMUHIJZXSF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25ClN2OS/c23-18-10-8-17(9-11-18)22(26)12-15-25(16-13-22)14-4-3-7-21-24-19-5-1-2-6-20(19)27-21/h1-2,5-6,8-11,26H,3-4,7,12-16H2
PubChem CID	60167309
ChEMBL	CHEMBL2037432
IUPHAR	N/A
BindingDB	50384970
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
54513	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
54511	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
54512	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
54510	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
523119	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
54509	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
523118	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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