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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL179757
Molecular formula	C27H31N3O
IUPAC name	N-[4-(1,2,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-3-yl)butyl]naphthalene-2-carboxamide
Molecular weight	413.565
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.3
Synonyms	Naphthalene-2-carboxylic acid [4-(1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide BDBM50162869 N-(4-(1,2,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-3-yl)butyl)-2-naphthamide
Inchi Key	KIVKVDKAEVGINM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H31N3O/c31-27(24-12-11-21-7-1-2-9-23(21)19-24)28-15-5-6-16-29-17-18-30-25(20-29)14-13-22-8-3-4-10-26(22)30/h1-4,7-12,19,25H,5-6,13-18,20H2,(H,28,31)
PubChem CID	9801858
ChEMBL	CHEMBL179757
IUPHAR	N/A
BindingDB	50162869
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
170120	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
170119	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
170121	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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