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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1940405
Molecular formula	C20H23ClFNS
IUPAC name	4-(4-chlorophenyl)-1-[3-(4-fluorophenyl)sulfanylpropyl]piperidine
Molecular weight	363.919
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.8
Synonyms	BDBM50362869
Inchi Key	CXHLKGHIDPMPHM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23ClFNS/c21-18-4-2-16(3-5-18)17-10-13-23(14-11-17)12-1-15-24-20-8-6-19(22)7-9-20/h2-9,17H,1,10-15H2
PubChem CID	57394810
ChEMBL	CHEMBL1940405
IUPHAR	N/A
BindingDB	50362869
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52798	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
52799	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
52797	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
52795	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
52796	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
52794	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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