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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3818047
Molecular formula	C19H20ClNO
IUPAC name	1-(4-chlorophenyl)-4-(3,4-dihydro-1H-isoquinolin-2-yl)butan-1-one
Molecular weight	313.825
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	4.1
Synonyms	J3.555.138G 1-(4-Chlorophenyl)-4-[3,4-dihydroisoquinoline-2(1H)-yl]-1-butanone SCHEMBL20364978 BDBM50182742
Inchi Key	HKUPNFQZELWUIO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H20ClNO/c20-18-9-7-16(8-10-18)19(22)6-3-12-21-13-11-15-4-1-2-5-17(15)14-21/h1-2,4-5,7-10H,3,6,11-14H2
PubChem CID	91864602
ChEMBL	CHEMBL3818047
IUPHAR	N/A
BindingDB	50182742
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
524925	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
524924	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
524927	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
524930	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
524928	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
524922	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
524929	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
524923	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
524926	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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