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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL193300
Molecular formula	C31H38N4O2
IUPAC name	N-[1-[2-[(4aS)-8-methoxy-1,2,4,4a,5,6-hexahydropyrazino[1,2-a]quinolin-3-yl]ethyl]piperidin-4-yl]naphthalene-2-carboxamide
Molecular weight	498.671
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.1
Synonyms	Naphthalene-2-carboxylic acid {1-[2-((S)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-ethyl]-piperidin-4-yl}-amide BDBM50166021
Inchi Key	DVXDATODDZJCOX-NDEPHWFRSA-N
Inchi ID	InChI=1S/C31H38N4O2/c1-37-29-10-11-30-25(21-29)8-9-28-22-34(18-19-35(28)30)17-16-33-14-12-27(13-15-33)32-31(36)26-7-6-23-4-2-3-5-24(23)20-26/h2-7,10-11,20-21,27-28H,8-9,12-19,22H2,1H3,(H,32,36)/t28-/m0/s1
PubChem CID	11454813
ChEMBL	CHEMBL193300
IUPHAR	N/A
BindingDB	50166021
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
70330	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
70328	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
70329	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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