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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL345820
Molecular formula	C26H29Cl2N3O2
IUPAC name	N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]-1-methoxynaphthalene-2-carboxamide
Molecular weight	486.437
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.0
Synonyms	BDBM50122041 N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)-1-methoxy-2-naphthamide 1-Methoxy-naphthalene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide
Inchi Key	JIFZJJHUCHFIGP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H29Cl2N3O2/c1-33-25-20-8-3-2-7-19(20)11-12-21(25)26(32)29-13-4-5-14-30-15-17-31(18-16-30)23-10-6-9-22(27)24(23)28/h2-3,6-12H,4-5,13-18H2,1H3,(H,29,32)
PubChem CID	10961938
ChEMBL	CHEMBL345820
IUPHAR	N/A
BindingDB	50122041
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
151598	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
151599	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
151604	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
151605	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
151600	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
151601	D(3) dopamine receptor	P19020	Drd3	Rattus norvegicus (Rat)	446
151602	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
151603	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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