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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3289642
Molecular formula	C21H22ClFN2O
IUPAC name	2-[2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl]-5-fluoro-2,3-dihydroinden-1-one
Molecular weight	372.868
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.4
Synonyms	BDBM50017966
Inchi Key	JLUQWCZYPJKNMK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22ClFN2O/c22-17-1-4-19(5-2-17)25-11-9-24(10-12-25)8-7-15-13-16-14-18(23)3-6-20(16)21(15)26/h1-6,14-15H,7-13H2
PubChem CID	90644058
ChEMBL	CHEMBL3289642
IUPHAR	N/A
BindingDB	50017966
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
153990	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
153991	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
153988	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
153989	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
153992	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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