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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1946253
Molecular formula	C21H26ClFN2
IUPAC name	1-(4-chlorophenyl)-4-[4-(4-fluorophenyl)butyl]-1,4-diazepane
Molecular weight	360.901
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	5.6
Synonyms	BDBM50363896
Inchi Key	FVMDOYQNOWAVCQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H26ClFN2/c22-19-7-11-21(12-8-19)25-15-3-14-24(16-17-25)13-2-1-4-18-5-9-20(23)10-6-18/h5-12H,1-4,13-17H2
PubChem CID	57345619
ChEMBL	CHEMBL1946253
IUPHAR	N/A
BindingDB	50363896
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
88308	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
88309	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
88305	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
88307	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
88311	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
88306	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
88310	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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