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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3986927
Molecular formula	C21H22N2O2
IUPAC name	5-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butanoyl]-1,3-dihydroindol-2-one
Molecular weight	334.419
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.3
Synonyms	SCHEMBL20359110 BDBM50199125
Inchi Key	GJUWVTJJMMQPAO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22N2O2/c24-20(16-7-8-19-18(12-16)13-21(25)22-19)6-3-10-23-11-9-15-4-1-2-5-17(15)14-23/h1-2,4-5,7-8,12H,3,6,9-11,13-14H2,(H,22,25)
PubChem CID	134156222
ChEMBL	CHEMBL3986927
IUPHAR	N/A
BindingDB	50199125
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
549072	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
549070	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
549071	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
549074	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
549069	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
549067	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
549068	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
549073	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
549075	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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