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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1940420
Molecular formula	C18H22FN3O
IUPAC name	1-[3-(4-fluorophenoxy)propyl]-4-pyridin-2-ylpiperazine
Molecular weight	315.392
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	BDBM50362865 L003777 AKOS017132342
Inchi Key	BPDDCCYSOYRMEC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22FN3O/c19-16-5-7-17(8-6-16)23-15-3-10-21-11-13-22(14-12-21)18-4-1-2-9-20-18/h1-2,4-9H,3,10-15H2
PubChem CID	44209472
ChEMBL	CHEMBL1940420
IUPHAR	N/A
BindingDB	50362865
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29416	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
29411	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
29418	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
29417	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
29410	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
29419	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
29413	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
29412	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
29420	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
29415	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
29414	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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