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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3321789
Molecular formula	C22H25ClFNO2
IUPAC name	3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol
Molecular weight	389.895
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50055520
Inchi Key	AWIYLVWAILOVMX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H25ClFNO2/c23-17-4-2-16(3-5-17)22(26)14-19-8-9-20(15-22)25(19)12-1-13-27-21-10-6-18(24)7-11-21/h2-7,10-11,19-20,26H,1,8-9,12-15H2
PubChem CID	13091356
ChEMBL	CHEMBL3321789
IUPHAR	N/A
BindingDB	50055520
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
442280	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
442281	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
442285	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
442282	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
442278	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
442284	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
442283	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
442279	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
442287	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
442286	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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