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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1946122
Molecular formula	C22H25ClFNO2
IUPAC name	(1S,5R)-3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol
Molecular weight	389.895
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.8
Synonyms	BDBM50363903
Inchi Key	AWIYLVWAILOVMX-RLAPIPATSA-N
Inchi ID	InChI=1S/C22H25ClFNO2/c23-17-4-2-16(3-5-17)22(26)14-19-8-9-20(15-22)25(19)12-1-13-27-21-10-6-18(24)7-11-21/h2-7,10-11,19-20,26H,1,8-9,12-15H2/t19-,20+,22?
PubChem CID	13091358
ChEMBL	CHEMBL1946122
IUPHAR	N/A
BindingDB	50363903
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16073	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
16074	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
16076	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
16075	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
16078	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
16077	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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