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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(4) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd4
Synonym	D(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4
Disease	N/A for non-human GPCRs
Length	387
Amino acid sequence	MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
UniProt	P30729
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3361
IUPHAR	217
DrugBank	N/A

Ligand

Name	CHEMBL3818669
Molecular formula	C20H20N2O2
IUPAC name	2-[4-(1,3-dihydroisoindol-2-yl)butyl]isoindole-1,3-dione
Molecular weight	320.392
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.3
Synonyms	BDBM50182744 SCHEMBL20358477
Inchi Key	CXXWGJNYYONTKW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H20N2O2/c23-19-17-9-3-4-10-18(17)20(24)22(19)12-6-5-11-21-13-15-7-1-2-8-16(15)14-21/h1-4,7-10H,5-6,11-14H2
PubChem CID	127052466
ChEMBL	CHEMBL3818669
IUPHAR	N/A
BindingDB	50182744
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	1348.96 nM	PMID27312422	ChEMBL
Ki	1349.0 nM	PMID27312422	BindingDB
Ki	1361.0 nM	PMID27312422	BindingDB,ChEMBL

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