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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1940404
Molecular formula	C20H23ClFNO2
IUPAC name	4-(4-chlorophenyl)-1-[3-(4-fluorophenoxy)propyl]piperidin-4-ol
Molecular weight	363.857
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.6
Synonyms	BDBM50362868 JPTSMZMSIACDAD-UHFFFAOYSA-N 1-[3-(p-fluorophenoxy)-propyl]-4-(p-chlorophenyl)-4-hydroxypiperidine SCHEMBL11844101
Inchi Key	JPTSMZMSIACDAD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23ClFNO2/c21-17-4-2-16(3-5-17)20(24)10-13-23(14-11-20)12-1-15-25-19-8-6-18(22)7-9-19/h2-9,24H,1,10-15H2
PubChem CID	21527771
ChEMBL	CHEMBL1940404
IUPHAR	N/A
BindingDB	50362868
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
156887	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
156885	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
447891	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
447890	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
447892	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
447894	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
447889	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
156886	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
156889	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
156888	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
447893	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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