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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(4) dopamine receptor
Species	Rattus norvegicus (Rat)
Gene	Drd4
Synonym	D(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4
Disease	N/A for non-human GPCRs
Length	387
Amino acid sequence	MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASERILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVCCLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRKRGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC
UniProt	P30729
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3361
IUPHAR	217
DrugBank	N/A

Ligand

Name	BRN 4530212
Molecular formula	C19H23FN2O
IUPAC name	1-[3-(4-fluorophenoxy)propyl]-4-phenylpiperazine
Molecular weight	314.404
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.0
Synonyms	1-[3-(4-fluorophenoxy)propyl]-4-phenylpiperazine DTXSID30233304 AC1MIH73 LS-112656 BDBM50362857 1-(3-(4-Fluorophenoxy)propyl)-4-phenylpiperazine CHEMBL1940412 84344-34-3 Piperazine, 1-(3-(4-fluorophenoxy)propyl)-4-phenyl- [ Show all ]
Inchi Key	GUOQPFNLBAXWIZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23FN2O/c20-17-7-9-19(10-8-17)23-16-4-11-21-12-14-22(15-13-21)18-5-2-1-3-6-18/h1-3,5-10H,4,11-16H2
PubChem CID	3069135
ChEMBL	CHEMBL1940412
IUPHAR	N/A
BindingDB	50362857
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	7.4 nM	PMID22245230	BindingDB,ChEMBL

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