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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1940415
Molecular formula	C18H23FN4
IUPAC name	2-[4-[4-(4-fluorophenyl)butyl]piperazin-1-yl]pyrimidine
Molecular weight	314.408
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50362860
Inchi Key	GTBFEJIEYNPFMI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H23FN4/c19-17-7-5-16(6-8-17)4-1-2-11-22-12-14-23(15-13-22)18-20-9-3-10-21-18/h3,5-10H,1-2,4,11-15H2
PubChem CID	57393083
ChEMBL	CHEMBL1940415
IUPHAR	N/A
BindingDB	50362860
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
104670	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
104665	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
104669	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
104667	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
104666	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
104668	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
104671	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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