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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ABT-724
Molecular formula	C17H19N5
IUPAC name	2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-benzimidazole
Molecular weight	293.374
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.2
Synonyms	ABT 724 CHEBI:104134 KS-00002WSL SR-01000050272 2-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-1H-benzoimidazole 2-{[4-(pyridin-2-yl)piperazin-1-yl]methyl}-1H-1,3-benzodiazole AC1NMGX9 D03TNA MCULE-3633641507 Z55621861 BEN800 FT-0737091 SCHEMBL1448486 2-((4-(pyridin-2-yl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole KSC-15-042 SR-01000050272-1 2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-benzimidazole 474417-17-9 AKOS015994554 ES-0001 MLS001233669 ZINC25427051 1H-Benzimidazole, 2-((4-(2-pyridinyl)-1-piperazinyl)methyl)- 70006-24-5 BRD-K37714784-305-01-3 HMS2888K18 SMR000592214 2-((4-Pyridin-2-ylpiperazine-1-yl)methyl)-1H-benzimidazole ABT724 CHEMBL440687 KUC105568N UNII-4WV2575JWT 2-[4-(2-Pyridyl)piperazin-1-ylmethyl]-1H-benzimidazole maleate 4WV2575JWT BDBM50145075 FRPJGTNLZNXQEX-UHFFFAOYSA-N MolPort-001-728-583 1H-Benzimidazole, 2-[[4-(2-pyridinyl)-1-piperazinyl]methyl]- [ Show all ]
Inchi Key	FRPJGTNLZNXQEX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H19N5/c1-2-6-15-14(5-1)19-16(20-15)13-21-9-11-22(12-10-21)17-7-3-4-8-18-17/h1-8H,9-13H2,(H,19,20)
PubChem CID	5025739
ChEMBL	CHEMBL440687
IUPHAR	N/A
BindingDB	50145075
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
85594	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
85597	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
85595	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
85596	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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