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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3818989
Molecular formula	C19H21NO
IUPAC name	4-(3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylbutan-1-one
Molecular weight	279.383
Hydrogen bond acceptor	2
Hydrogen bond donor	0
XlogP	3.5
Synonyms	BDBM50182748 SCHEMBL20358752 AKOS009059953
Inchi Key	KAHXPONUPROIRS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21NO/c21-19(17-8-2-1-3-9-17)11-6-13-20-14-12-16-7-4-5-10-18(16)15-20/h1-5,7-10H,6,11-15H2
PubChem CID	43229249
ChEMBL	CHEMBL3818989
IUPHAR	N/A
BindingDB	50182748
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
526206	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
526214	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
526208	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
526213	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
526211	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
526209	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
526207	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
526210	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387
526212	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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